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The Journal of Biological Chemistry|April 17, 2013
Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptorBrian D Hudson, Maria E Due-Hansen, Elisabeth Christiansen, et al.Journal of Medicinal Chemistry|August 30, 2016
Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic ActivityCarlos M G Azevedo, Kenneth R Watterson, Ed T Wargent, et al.Diabetologia|May 22, 2023
Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse isletsEstela Lorza-Gil, Gabriele Kaiser, Christopher Carlein, et al.Journal of Medicinal Chemistry|February 21, 2024
Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 AgonistsLoukas Ieremias, Mads H Kaspersen, Asmita Manandhar, et al.ACS Medicinal Chemistry Letters|May 21, 2013
Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 DiabetesElisabeth Christiansen, Steffen V F Hansen, Christian Urban, et al.Molecular Metabolism|October 22, 2020
Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WATAnna Sofie Husted, Jeppe H Ekberg, Emma Tripp, et al.The British Journal of Nutrition|April 29, 2015
Activity of dietary fatty acids on FFA1 and FFA4 and characterisation of pinolenic acid as a dual FFA1/FFA4 agonist with potential effect against metabolic diseasesElisabeth Christiansen, Kenneth R Watterson, Claire J Stocker, et al.Journal of Medicinal Chemistry|January 9, 2013
Discovery of a potent and selective free fatty acid receptor 1 agonist with low lipophilicity and high oral bioavailabilityElisabeth Christiansen, Maria E Due-Hansen, Christian Urban, et al.Journal of Medicinal Chemistry|March 2, 2016
Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area, and Robust in Vivo EfficacySteffen V F Hansen, Elisabeth Christiansen, Christian Urban, et al.Nature Chemical Biology|May 29, 2012
A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimerStefanie Blättermann, Lucas Peters, Philipp Aaron Ottersbach, et al.Pageof 12