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Future Medicinal Chemistry|March 22, 2014
Potential strategies for increasing drug-discovery productivityJohn G Cumming, M Raymond V Finlay, Fabrizio Giordanetto, et al.Antimicrobial Agents and Chemotherapy|July 3, 2019
Safety, Tolerability, Pharmacokinetics, and Drug Interaction Potential of SPR741, an Intravenous Potentiator, after Single and Multiple Ascending Doses and When Combined with β-Lactam Antibiotics in Healthy SubjectsPaul B Eckburg, Troy Lister, Susannah Walpole, et al.ACS Infectious Diseases|October 1, 2019
Potentiation of Antibiotics against Gram-Negative Bacteria by Polymyxin B Analogue SPR741 from Unique Perturbation of the Outer MembraneShawn French, Maya Farha, Michael J Ellis, et al.Antimicrobial Agents and Chemotherapy|May 24, 2017
Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741David Corbett, Andrew Wise, Tara Langley, et al.Journal of the American Chemical Society|September 6, 2008
Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexityK C Nicolaou, Antonia F Stepan, Troy Lister, et al.Antimicrobial Agents and Chemotherapy|September 27, 2017
SPR741, an Antibiotic Adjuvant, Potentiates the In Vitro and In Vivo Activity of Rifampin against Clinically Relevant Extensively Drug-Resistant Acinetobacter baumanniiDaniel V Zurawski, Alexandria A Reinhart, Yonas A Alamneh, et al.Antibiotics (Basel, Switzerland)|September 23, 2022
Minocycline and the SPR741 Adjuvant Are an Efficacious Antibacterial Combination for Acinetobacter baumannii InfectionsYonas A Alamneh, Vlado Antonic, Brittany Garry, et al.ACS Omega|February 21, 2022
High-Throughput Screen for Inhibitors of Klebsiella pneumoniae Virulence Using a Tetrahymena pyriformis Co-Culture Surrogate Host ModelAngela L Woods, David Parker, Meir M Glick, et al.Cytotherapy|July 5, 2025
Advancing gene-editing platforms to improve the viability of rare-disease therapeutics: key insights from a 2024 Scientific Exchange hosted by ARM, ISCT, and DanaherFyodor Urnov, Sadik Kassim, Kiran Musunuru, et al.Journal of Medicinal Chemistry|February 10, 2012
Discovery of LFF571: an investigational agent for Clostridium difficile infectionMatthew J LaMarche, Jennifer A Leeds, Adam Amaral, et al.Pageof 3