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Xenobiotica; the Fate of Foreign Compounds in Biological Systems|September 28, 2022
Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-KNaotoshi Yamamura, Tsuyoshi Mikkaichi, Ken-Ichi Itokawa, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 25, 2014
Edoxaban transport via P-glycoprotein is a key factor for the drug's dispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, et al.International Journal of Pharmaceutics|February 5, 2021
Quantitative analysis of an impact of P-glycoprotein on edoxaban's disposition using a human physiologically based pharmacokinetic (PBPK) modelTakafumi Kato, Tsuyoshi Mikkaichi, Yasushi Yoshigae, et al.Drug Metabolism and Pharmacokinetics|July 9, 2010
Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1Hiroaki Yamaguchi, Misa Sugie, Masahiro Okada, et al.Pharmaceutical Research|November 9, 2014
Evaluation of the usefulness of breast cancer resistance protein (BCRP) knockout mice and BCRP inhibitor-treated monkeys to estimate the clinical impact of BCRP modulation on the pharmacokinetics of BCRP substratesTsuyoshi Karibe, Rie Hagihara-Nakagomi, Koji Abe, et al.Journal of Gastroenterology|June 3, 2006
Farnesoid X receptor, hepatocyte nuclear factors 1alpha and 3beta are essential for transcriptional activation of the liver-specific organic anion transporter-2 geneHideo Ohtsuka, Takaaki Abe, Tohru Onogawa, et al.Bioorganic & Medicinal Chemistry Letters|April 23, 2013
Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitorsTaiji Goto, Akiko Shiina, Toshiharu Yoshino, et al.Bioorganic & Medicinal Chemistry|October 8, 2013
Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitorsTaiji Goto, Akiko Shiina, Toshiharu Yoshino, et al.Journal of Pharmacological Sciences|October 25, 2013
Evaluation of the therapeutic index of a novel phosphodiesterase 4B-selective inhibitor over phosphodiesterase 4D in miceOsamu Suzuki, Kiyoshi Mizukami, Maki Etori, et al.Investigative Ophthalmology & Visual Science|October 28, 2003
Distribution of rat organic anion transporting polypeptide-E (oatp-E) in the rat eyeAki Ito, Katsuhiro Yamaguchi, Hiroshi Tomita, et al.Pageof 3