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Frontiers in Pharmacology
|
August 15, 2014
Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research
Tove Tuntland, Brian Ethell, Takatoshi Kosaka, et al.
Journal of Medicinal Chemistry
|
July 25, 2013
Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases
Michael D Shultz, Dyuti Majumdar, Donovan N Chin, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
April 6, 2006
Tumor targeting by an aptamer
Brian J Hicke, Andrew W Stephens, Ty Gould, et al.
Molecular and Cellular Biology
|
October 31, 2012
Defective autophagy and mTORC1 signaling in myotubularin null mice
Kristina M Fetalvero, Yenyen Yu, Margaret Goetschkes, et al.
ACS Medicinal Chemistry Letters
|
July 24, 2018
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors
Qian Zhao, James R Manning, James Sutton, et al.
ACS Medicinal Chemistry Letters
|
October 24, 2017
Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor
Young Shin Cho, Julian R Levell, Gang Liu, et al.
Nature Chemical Biology
|
November 4, 2016
Small-molecule factor D inhibitors targeting the alternative complement pathway
Jürgen Maibaum, Sha-Mei Liao, Anna Vulpetti, et al.
ACS Medicinal Chemistry Letters
|
February 16, 2017
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1
Julian R Levell, Thomas Caferro, Gregg Chenail, et al.
Journal of Medicinal Chemistry
|
July 13, 2013
Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor
Michael D Shultz, Atwood K Cheung, Christina A Kirby, et al.
Page
of 1
Search research articles
Search
Showing results (1-10 of 9) with videos related to
Sort By:
Page
of 1
Frontiers in Pharmacology
|
August 15, 2014
Implementation of pharmacokinetic and pharmacodynamic strategies in early research phases of drug discovery and development at Novartis Institute of Biomedical Research
Tove Tuntland, Brian Ethell, Takatoshi Kosaka, et al.
Journal of Medicinal Chemistry
|
July 25, 2013
Structure-efficiency relationship of [1,2,4]triazol-3-ylamines as novel nicotinamide isosteres that inhibit tankyrases
Michael D Shultz, Dyuti Majumdar, Donovan N Chin, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
April 6, 2006
Tumor targeting by an aptamer
Brian J Hicke, Andrew W Stephens, Ty Gould, et al.
Molecular and Cellular Biology
|
October 31, 2012
Defective autophagy and mTORC1 signaling in myotubularin null mice
Kristina M Fetalvero, Yenyen Yu, Margaret Goetschkes, et al.
ACS Medicinal Chemistry Letters
|
July 24, 2018
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors
Qian Zhao, James R Manning, James Sutton, et al.
ACS Medicinal Chemistry Letters
|
October 24, 2017
Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor
Young Shin Cho, Julian R Levell, Gang Liu, et al.
Nature Chemical Biology
|
November 4, 2016
Small-molecule factor D inhibitors targeting the alternative complement pathway
Jürgen Maibaum, Sha-Mei Liao, Anna Vulpetti, et al.
ACS Medicinal Chemistry Letters
|
February 16, 2017
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1
Julian R Levell, Thomas Caferro, Gregg Chenail, et al.
Journal of Medicinal Chemistry
|
July 13, 2013
Identification of NVP-TNKS656: the use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor
Michael D Shultz, Atwood K Cheung, Christina A Kirby, et al.
Page
of 1