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Biorxiv : the Preprint Server for Biology|December 9, 2024
Deep Learning of Cellular Metabolic Flux Distributions Predicts LifespanTyler A U Hilsabeck, Shane L Rea
Aging Cell|September 14, 2021
S3QELs protect against diet-induced intestinal barrier dysfunctionMark A Watson, Blaine Pattavina, Tyler A U Hilsabeck, et al.
Biorxiv : the Preprint Server for Biology|July 28, 2023
Systems biology and machine learning approaches identify metabolites that influence dietary lifespan and healthspan responses across flies and humansTyler A U Hilsabeck, Vikram P Narayan, Kenneth A Wilson, et al.
Nature Communications|October 30, 2024
Systems biology approaches identify metabolic signatures of dietary lifespan and healthspan across speciesTyler A U Hilsabeck, Vikram P Narayan, Kenneth A Wilson, et al.
Aging|March 21, 2025
Inhibition of the metalloprotease ADAM19 as a novel senomorphic strategy to ameliorate gut permeability and senescence markers by modulating senescence-associated secretory phenotype (SASP)Sudipta Bar, Tyler A U Hilsabeck, Blaine Pattavina, et al.
Frontiers in Genetics|October 18, 2021
Mifepristone Increases Life Span of Virgin Female <i>Drosophila</i> on Regular and High-fat Diet Without Reducing Food IntakeGary N Landis, Tyler A U Hilsabeck, Hans S Bell, et al.
Biorxiv : the Preprint Server for Biology|May 4, 2026
Cellular senescence dysregulates antiviral interferon responses in idiopathic pulmonary fibrosisJun-Wei B Hughes, Yasmina Reisser, Franziska Hornung, et al.
Geroscience|April 6, 2022
A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory responseTyler A U Hilsabeck, Ru Liu-Bryan, Tracy Guo, et al.
Research Square|November 21, 2023
Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress ReductionSudipta Bar, Kenneth A Wilson, Tyler A U Hilsabeck, et al.
Nature Metabolism|June 30, 2025
Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reductionSudipta Bar, Kenneth A Wilson, Tyler A U Hilsabeck, et al.
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