Showing results (1-10 of 33) with videos related to

Sort By:
Pageof 4
The Journal of Biological Chemistry|June 16, 2019
A driving test for oncogenic mutationsDavid E Heppner, Tyler S Beyett, Michael J Eck
Biorxiv : the Preprint Server for Biology|July 3, 2026
Structural and Biochemical Analysis of the CABIT1 Domain of THEMISKristos I Negrón Terón, Daniela Ortiz Salazar, Tyler S Beyett
Chemmedchem|March 24, 2024
Structural Analysis of the Macrocyclic Inhibitor BI-4020 Binding to EGFR KinaseTyler S Beyett, Jaimin K Rana, Ilse K Schaeffner, et al.
Methods in Enzymology|May 28, 2023
Structural elements that enable specificity for mutant EGFR kinase domains with next-generation small-molecule inhibitorsTahereh Damghani, Florian Wittlinger, Tyler S Beyett, et al.
Protein Expression and Purification|December 2, 2019
Characterization of a hyperphosphorylated variant of G protein-coupled receptor kinase 5 expressed in E. coliTyler S Beyett, Qiuyan Chen, Emily J Labudde, et al.
The Journal of Biological Chemistry|August 16, 2017
Navigating the conformational landscape of G protein-coupled receptor kinases during allosteric activationXin-Qiu Yao, M Claire Cato, Emily Labudde, et al.
Molecular Pharmacology|January 2, 2024
A Constitutive EGFR Kinase Dimer to Study Inhibitor PharmacologyJustin J Kim, Ilse K Schaeffner, David E Heppner, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 29, 2024
Biochemical analysis of EGFR exon20 insertion variants insASV and insSVD and their inhibitor sensitivityHanchen Zhao, Tyler S Beyett, Jie Jiang, et al.
The Journal of Biological Chemistry|March 24, 2023
Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenibEmre Tkacik, Kunhua Li, Gonzalo Gonzalez-Del Pino, et al.
Bioorganic & Medicinal Chemistry|October 2, 2018
Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesityTyler S Beyett, Xinmin Gan, Shannon M Reilly, et al.
Pageof 4