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RSC Chemical Biology|February 13, 2025
Bioinformatic, structural, and biochemical analysis leads to the discovery of novel isonitrilases and decodes their substrate selectivityTyler Hostetler, Tzu-Yu Chen, Wei-Chen ChangMethods in Enzymology|September 20, 2024
Cyclopropanation and aziridination catalyzed by non-heme iron and 2-oxoglutarate dependent enzymesTzu-Yu Chen, Lide Cha, Jared C Paris, et al.Chinese Journal of Chemistry|October 18, 2021
Current Understanding toward Isonitrile Group Biosynthesis and MechanismTzu-Yu Chen, Jinfeng Chen, Yijie Tang, et al.Angewandte Chemie (International Ed. in English)|February 20, 2020
Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent OxygenasesTzu-Yu Chen, Jinfeng Chen, Yijie Tang, et al.ACS Catalysis|September 2, 2025
Studies of Isonitrile Synthases Help Elucidate the Mechanism of Isonitrile InstallationTzu-Yu Chen, Wantae Kim, Mo Guo, et al.Journal of the American Chemical Society|August 5, 2025
Multiple Catalytic Branch Points in the Mechanism of Pyrrolidine Formation During Kainoid Biosynthesis Leads to Diverse Reaction OutcomesTzu-Yu Chen, Mark W Ruszczycky, Angela Yao, et al.Nature Communications|September 13, 2022
Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylateWantae Kim, Tzu-Yu Chen, Lide Cha, et al.ACS Catalysis|June 19, 2024
Variation in biosynthesis and metal-binding properties of isonitrile-containing peptides produced by Mycobacteria versus StreptomycesTzu-Yu Chen, Jinfeng Chen, Mark W Ruszczycky, et al.Journal of the American Chemical Society|June 6, 2025
An Alternative Mechanism for C-C Desaturation Underscores a Dual-Controlled Mechanism for the Fate of Radical Intermediate in Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenase DfmDXuan Zhang, Lanteng Wang, Jia Liu, et al.Biochemistry|April 15, 2025
Beyond the β-α-β Fold: Characterization of a SnoaL Domain in the Tautomerase SuperfamilyTrevor R Melkonian, Nemanja Vuksanovic, Maria D Person, et al.Pageof 15