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Environmental Health Perspectives|April 12, 2021
Profiling the Tox21 Chemical Collection for Acetylcholinesterase InhibitionShuaizhang Li, Jinghua Zhao, Ruili Huang, et al.Plos Pathogens|November 19, 2013
Turning defense into offense: defensin mimetics as novel antibiotics targeting lipid IIKristen M Varney, Alexandre M J J Bonvin, Marzena Pazgier, et al.Journal of the American Chemical Society|February 16, 2016
Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click ChemistryIan Glassford, Christiana N Teijaro, Samer S Daher, et al.Journal of Computational Chemistry|November 19, 2016
CHARMM-GUI 10 years for biomolecular modeling and simulationSunhwan Jo, Xi Cheng, Jumin Lee, et al.Molecular Cancer|May 18, 2013
The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with BakXiaobo Cao, Jeremy L Yap, M Karen Newell-Rogers, et al.Organic & Biomolecular Chemistry|April 30, 2013
Structural modifications of (Z)-3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione that improve selectivity for inhibiting the proliferation of melanoma cells containing active ERK signalingKwan-Young Jung, Ramin Samadani, Jay Chauhan, et al.The Journal of Pharmacology and Experimental Therapeutics|February 19, 2025
First-in-class mitogen-activated protein kinase (MAPK) p38α: MAPK-activated protein kinase 2 dual signal modulator with anti-inflammatory and endothelial-stabilizing propertiesMohan E Tulapurkar, Kari Ann Shirey, Katerina Lugkey, et al.The Journal of Pharmacology and Experimental Therapeutics|September 16, 2024
First-in-Class Mitogen-Activated Protein Kinase p38α: MAPK-Activated Protein Kinase-2 (MK2) Dual Signal Modulator with Anti-inflammatory and Endothelial-stabilizing PropertiesMohan E Tulapurkar, Kari Ann Shirey, Katerina N Lugkey, et al.Cancer Research|May 20, 2016
The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress TumorigenesisLuisana Astudillo, Thiago G Da Silva, Zhiqiang Wang, et al.Cancer Cell|April 14, 2010
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivoLeandro C Cerchietti, Alexandru F Ghetu, Xiao Zhu, et al.Pageof 49