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Neuron|October 12, 2018
Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's DiseaseSilke Nuber, Molly Rajsombath, Georgia Minakaki, et al.
Results in Chemistry|June 22, 2023
Discovery of 4-aminoindole carboxamide derivatives to curtail alpha-synuclein and tau isoform 2N4R oligomer formationEduardo Ramirez, Sehong Min, Susantha K Ganegamage, et al.
International Journal of Molecular Sciences|July 26, 2020
Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase InhibitorElizabeth Terry-Kantor, Arati Tripathi, Thibaut Imberdis, et al.
Bioorganic & Medicinal Chemistry|November 17, 2024
Exploring the rhodanine universe: Design and synthesis of fluorescent rhodanine-based derivatives as anti-fibrillar and anti-oligomer agents against α-synuclein and 2N4R tauAhmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, et al.
ACS Omega|March 3, 2025
Inspecting the Triazole Scaffold as Powerful Antifibril Agents against 2N4R Tau and α-Synuclein AggregatesAhmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, et al.
NPJ Parkinson'S Disease|September 16, 2022
Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neuronsLuis Fonseca-Ornelas, Jonathan M S Stricker, Stephanie Soriano-Cruz, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|January 28, 2022
Pathogenic Mechanisms of Cytosolic and Membrane-Enriched α-Synuclein Converge on Fatty Acid HomeostasisArati Tripathi, Heba Alnakhala, Elizabeth Terry-Kantor, et al.
ACS Omega|January 15, 2024
1,4-Diurea- and 1,4-Dithiourea-Substituted Aromatic Derivatives Selectively Inhibit α-Synuclein Oligomer Formation <i>In Vitro</i>Susantha K Ganegamage, Eduardo Ramirez, Heba Alnakhala, et al.
NPJ Parkinson'S Disease|May 21, 2024
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neuronsAndrew J White, Karis A Clark, Kellianne D Alexander, et al.
ACS Omega|June 12, 2023
5-Nitro-1,2-benzothiazol-3-amine and <i>N</i>-Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau AggregationEduardo Ramirez, Susantha K Ganegamage, Ahmed A Elbatrawy, et al.
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