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Bioorganic & Medicinal Chemistry Letters|December 26, 2017
Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screenDaniel S Palacios, Erik Meredith, Toshio Kawanami, et al.
Drug Metabolism Reviews|August 23, 2023
Bioactivation and reactivity research advances - 2022 year in review‡Shuai Wang, Upendra A Argikar, Lionel Cheruzel, et al.
Drug Metabolism Reviews|September 22, 2023
Biotransformation research advances - 2022 year in reviewS Cyrus Khojasteh, Upendra A Argikar, Lionel Cheruzel, et al.
Journal of Medicinal Chemistry|August 4, 2017
Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension ModelsKen Yamada, Julian Levell, Taeyong Yoon, et al.
Journal of Medicinal Chemistry|June 17, 2017
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in VivoEdwige Lorthiois, Karen Anderson, Anna Vulpetti, et al.
Clinical Pharmacology and Therapeutics|March 20, 2026
Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging TrendsJason Boer, Ellen Cannady, Filip Cuyckens, et al.
Journal of Medicinal Chemistry|April 18, 2019
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement PathwayRajeshri G Karki, James Powers, Nello Mainolfi, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 31, 2019
Small-molecule factor B inhibitor for the treatment of complement-mediated diseasesAnna Schubart, Karen Anderson, Nello Mainolfi, et al.
Journal of Medicinal Chemistry|February 20, 2020
Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated DiseasesNello Mainolfi, Takeru Ehara, Rajeshri G Karki, et al.
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