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ACS Medicinal Chemistry Letters|June 22, 2019
Discovery of Orally Active Hydroxyethylamine Based SPPL2a InhibitorsJuraj Velcicky, Casey J N Mathison, Victor Nikulin, et al.The Journal of Experimental Medicine|December 26, 2012
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chainDaniel R Beisner, Petra Langerak, Albert E Parker, et al.Canadian Journal of Diabetes|July 12, 2025
Blood characteristics of patients with type 2 diabetes and response of their peripheral blood mononuclear cells to inhibitors of the NLRP3-inflammasome and caspase-1Joyce de Paula Souza, Justus S Fischer, Karine Jeanneau, et al.Clinical Therapeutics|September 7, 2018
The Safety and Antiviral Activity of BZF961 with or without Ritonavir in Patients Infected with Hepatitis C Virus: A Randomized, Multicenter TrialEric Lawitz, Mohamed Bidair, Thomas Marbury, et al.The Journal of Allergy and Clinical Immunology|October 16, 2025
Caspase 1-deficient humans survive into late adulthood despite dramatically lower canonical inflammasome activityJohn Dominy, Christopher Koch, Christelle Arnold, et al.Pageof 2