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Plos One|May 22, 2013
Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5Sebastian Seidl, Ursula Braun, Norbert Roos, et al.Adipocyte|February 28, 2014
Impairment of insulin-stimulated glucose transport and ERK activation by adipocyte-specific knockout of PKC-λ produces a phenotype characterized by diminished adiposity and enhanced insulin suppression of hepatic gluconeogenesisMini P Sajan, Michael J Jurzak, Varman T Samuels, et al.Advances in Biological Regulation|September 29, 2020
Investigations of mouse models during tumorigenesis revealed essential but distinct in vivo functions among the PKC familyMichael LeitgesJournal of Lipid Research|February 10, 2009
The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesityMini P Sajan, Mary L Standaert, Sonali Nimal, et al.Diabetes|February 21, 2016
Brain Insulin Signaling Is Increased in Insulin-Resistant States and Decreases in FOXOs and PGC-1α and Increases in Aβ1-40/42 and Phospho-Tau May Abet Alzheimer DevelopmentMini Sajan, Barbara Hansen, Robert Ivey, et al.Metabolism: Clinical and Experimental|January 10, 2012
Correction of metabolic abnormalities in a rodent model of obesity, metabolic syndrome, and type 2 diabetes mellitus by inhibitors of hepatic protein kinase C-ιMini P Sajan, Sonali Nimal, Stephen Mastorides, et al.Neurobiology of Aging|October 17, 2017
Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's diseaseMini P Sajan, Barbara C Hansen, Margaret G Higgs, et al.Cancer Research|July 20, 2006
Protein kinase C alpha but not PKCzeta suppresses intestinal tumor formation in ApcMin/+ miceHenrik Oster, Michael LeitgesPlos One|April 3, 2026
Pan-cancer landscape of protein kinase D3: An integrative TCGA multi-omics analysis of clinical, molecular, and immunological rolesJocshan Loaiza-Moss, Michael LeitgesMolecular Endocrinology (Baltimore, Md.)|June 1, 2014
PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymesMini P Sajan, Robert A Ivey, Mackenzie Lee, et al.Pageof 22