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Methods in Molecular Biology (Clifton, N.J.)|August 9, 2023
Quality Control of Chemogenomic Library Using LC-MSVáclav Němec, Stefan KnappInternational Journal of Molecular Sciences|October 17, 2020
Cdc-Like Kinases (CLKs): Biology, Chemical Probes, and Therapeutic PotentialPaula Martín Moyano, Václav Němec, Kamil ParuchChemical Society Reviews|August 25, 2022
PROTAC degraders as chemical probes for studying target biology and target validationVáclav Němec, Martin P Schwalm, Susanne Müller, et al.European Journal of Medicinal Chemistry|February 26, 2021
Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine coreVáclav Němec, Lukáš Maier, Benedict-Tilman Berger, et al.JACS Au|September 1, 2021
A Chemical Toolbox for Labeling and Degrading Engineered Cas ProteinsRodrigo A Gama-Brambila, Jie Chen, Yasamin Dabiri, et al.Journal of the American Chemical Society|March 28, 2015
Site-specific analysis of protein hydration based on unnatural amino acid fluorescenceMariana Amaro, Jan Brezovský, Silvia Kováčová, et al.Journal of Medicinal Chemistry|December 27, 2024
Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/εAdrian Haag, Václav Němec, Pavlína Janovská, et al.ACS Chemical Biology|June 27, 2024
A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7Christian J Muñoz Sosa, Christopher Lenz, Anton Hamann, et al.Angewandte Chemie (International Ed. in English)|January 10, 2023
Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform SelectivityVáclav Němec, Prashant Khirsariya, Pavlína Janovská, et al.Angewandte Chemie (International Ed. in English)|December 21, 2018
Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog PathwayVáclav Němec, Michaela Hylsová, Lukáš Maier, et al.Pageof 2