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CPT: Pharmacometrics & Systems Pharmacology|February 3, 2025
Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsymJames J Beaudoin, Kyunghee Yang, Brett A Howell, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|May 7, 2026
RENAsym, a Quantitative Systems Toxicology Platform Model, Designed to Predict Drug-Induced Kidney Injury Indicates Polymyxin B and Valproate Overdose Toxicity Potential While Simultaneously Demonstrating Acetaminophen and Valproate Safety at Therapeutic LevelsCeleste Vallejo, Pallavi Bhargava, Nader Hamzavi, et al.Pharmacology Research & Perspectives|October 19, 2019
Quantitative systems toxicology (QST) reproduces species differences in PF-04895162 liver safety due to combined mitochondrial and bile acid toxicityGrant Generaux, Vinal V Lakhani, Yuching Yang, et al.Pageof 2