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Biochemistry|May 4, 2005
First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitorsMatthew D Lloyd, Nethaji Thiyagarajan, Yaik T Ho, et al.Nature Chemical Biology|August 12, 2009
Synthetic partial agonists reveal key steps in IP3 receptor activationAna M Rossi, Andrew M Riley, Stephen C Tovey, et al.Oncogene|February 3, 2004
Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathwayEnza Piccolo, Sara Vignati, Tania Maffucci, et al.Bioorganic & Medicinal Chemistry|March 11, 2008
Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for designGillian M Allan, Nigel Vicker, Harshani R Lawrence, et al.Journal of Medicinal Chemistry|February 13, 2010
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl templateL W Lawrence Woo, Toby Jackson, Aurélien Putey, et al.British Journal of Cancer|October 9, 2008
The in vivo properties of STX243: a potent angiogenesis inhibitor in breast cancerM F C Parsons, P A Foster, S K Chander, et al.British Journal of Cancer|January 22, 2009
BCRP expression does not result in resistance to STX140 in vivo, despite the increased expression of BCRP in A2780 cells in vitro after long-term STX140 exposureJ M Day, P A Foster, H J Tutill, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|March 1, 2023
Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodelingJi Qi, Weiwei Cheng, Zhe Gao, et al.Chemmedchem|July 16, 2010
Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activitiesPaul M Wood, L W Lawrence Woo, Jean-Robert Labrosse, et al.Cancer Research|January 7, 2006
The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cellsSimon P Newman, Christopher R Ireson, Helena J Tutill, et al.Pageof 69