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The Journal of Endocrinology|June 11, 2024
Does glucose-dependent insulinotropic polypeptide receptor blockade as well as agonism have a role to play in management of obesity and diabetes?Ryan A Lafferty, Peter R Flatt, Victor A Gault, et al.
Clinical Science (London, England : 1979)|February 22, 2011
Administration of an acylated GLP-1 and GIP preparation provides added beneficial glucose-lowering and insulinotropic actions over single incretins in mice with Type 2 diabetes and obesityVictor A Gault, Barry D Kerr, Patrick Harriott, et al.
Biochemical Pharmacology|May 6, 2008
C-terminal mini-PEGylation of glucose-dependent insulinotropic polypeptide exhibits metabolic stability and improved glucose homeostasis in dietary-induced diabetesVictor A Gault, Barry D Kerr, Nigel Irwin, et al.
Clinical Medicine Insights. Endocrinology and Diabetes|June 28, 2019
Effects of 2 Novel PYY(1-36) Analogues, (P3L31P34)PYY(1-36) and PYY(1-36)(Lys12PAL), on Pancreatic Beta-Cell Function, Growth, and SurvivalRyan A Lafferty, Victor A Gault, Peter R Flatt, et al.
The Journal of Biological Chemistry|October 30, 2013
A novel glucagon-like peptide-1 (GLP-1)/glucagon hybrid peptide with triple-acting agonist activity at glucose-dependent insulinotropic polypeptide, GLP-1, and glucagon receptors and therapeutic potential in high fat-fed miceVictor A Gault, Vikas K Bhat, Nigel Irwin, et al.
Calcified Tissue International|July 10, 2020
Dapagliflozin and Liraglutide Therapies Rapidly Enhanced Bone Material Properties and Matrix Biomechanics at Bone Formation Site in a Type 2 Diabetic Mouse ModelAleksandra Mieczkowska, Paul Millar, Daniel Chappard, et al.
Biochimica Et Biophysica Acta|March 23, 2013
A novel acylated form of (d-Ala(2))GIP with improved antidiabetic potential, lacking effect on body fat storesChristine M A Martin, Nigel Irwin, Peter R Flatt, et al.
Peptides|November 17, 2019
Blockade of gastric inhibitory polypeptide (GIP) action as a novel means of countering insulin resistance in the treatment of obesity-diabetesNigel Irwin, Victor A Gault, Finbarr P M O'Harte, et al.
Diabetologia|June 7, 2015
Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db miceVarun Pathak, Srividya Vasu, Victor A Gault, et al.
European Journal of Pharmacology|February 27, 2007
Soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learningChristian Holscher, Simon Gengler, Victor A Gault, et al.
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