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The Journal of Pharmacology and Experimental Therapeutics|May 29, 2012
Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune diseaseEric J Tarcha, Victor Chi, Ernesto J Muñoz-Elías, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 29, 2022
Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drugAnu Tyagi, Tofayel Ahmed, Shi Jian, et al.
The Journal of Clinical Investigation|February 18, 2004
Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxiaVikram G Shakkottai, Chin-hua Chou, Salvatore Oddo, et al.
Molecular Pharmacology|January 25, 2005
Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseasesChristine Beeton, Michael W Pennington, Heike Wulff, et al.
Ebiomedicine|August 20, 2022
Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpointNavin Kumar Verma, Brandon Han Siang Wong, Zhi Sheng Poh, et al.
British Journal of Cancer|November 22, 2017
The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cellsSerena Pillozzi, Massimo D'Amico, Gianluca Bartoli, et al.
European Journal of Immunology|December 9, 2024
High Extracellular K+ Skews T-Cell Differentiation Towards Tumour Promoting Th2 and Treg SubsetsBrandon Han Siang Wong, Zhi Sheng Poh, James Tan Chia Wei, et al.
The Journal of Clinical Investigation|August 9, 2008
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humansKazuyoshi Toyama, Heike Wulff, K George Chandy, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 5, 2013
Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistanceSanjeev Kumar Upadhyay, Kristin L Eckel-Mahan, M Reza Mirbolooki, et al.
Cancers|March 10, 2022
Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy ResponseJulian L Goggi, Shivashankar Khanapur, Boominathan Ramasamy, et al.
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