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Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Phosphoinositide-3-kinase inhibitors: evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511
Brian A Lanman, Anthony B Reed, Victor J Cee, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity
Lewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 14, 2007
Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors
Brian L Hodous, Stephanie D Geuns-Meyer, Paul E Hughes, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5
Victor J Cee, Mike Frohn, Brian A Lanman, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 9, 2008
Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase
Victor J Cee, Alan C Cheng, Karina Romero, et al.
Journal of Medicinal Chemistry
|
January 27, 2007
Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase
Victor J Cee, Brian K Albrecht, Stephanie Geuns-Meyer, et al.
Journal of Medicinal Chemistry
|
May 14, 2015
Discovery of N-(4-(3-(2-aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), a highly selective, orally bioavailable inhibitor of aurora kinases with activity against multidrug-resistant cancer cell lines
Stephanie Geuns-Meyer, Victor J Cee, Holly L Deak, et al.
ACS Medicinal Chemistry Letters
|
April 21, 2016
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors
Victor J Cee, Frank Chavez, Bradley Herberich, et al.
Journal of Medicinal Chemistry
|
January 27, 2007
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor
Brian L Hodous, Stephanie D Geuns-Meyer, Paul E Hughes, et al.
ACS Medicinal Chemistry Letters
|
September 19, 2019
Discovery of <i>N</i>-(1-Acryloylazetidin-3-yl)-2-(1<i>H</i>-indol-1-yl)acetamides as Covalent Inhibitors of KRAS<sup>G12C</sup>
Youngsook Shin, Joon Won Jeong, Ryan P Wurz, et al.
Page
of 4
Search research articles
Search
Showing results (21-30 of 40) with videos related to
Sort By:
Page
of 4
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Phosphoinositide-3-kinase inhibitors: evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511
Brian A Lanman, Anthony B Reed, Victor J Cee, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity
Lewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 14, 2007
Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors
Brian L Hodous, Stephanie D Geuns-Meyer, Paul E Hughes, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5
Victor J Cee, Mike Frohn, Brian A Lanman, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 9, 2008
Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase
Victor J Cee, Alan C Cheng, Karina Romero, et al.
Journal of Medicinal Chemistry
|
January 27, 2007
Alkynylpyrimidine amide derivatives as potent, selective, and orally active inhibitors of Tie-2 kinase
Victor J Cee, Brian K Albrecht, Stephanie Geuns-Meyer, et al.
Journal of Medicinal Chemistry
|
May 14, 2015
Discovery of N-(4-(3-(2-aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), a highly selective, orally bioavailable inhibitor of aurora kinases with activity against multidrug-resistant cancer cell lines
Stephanie Geuns-Meyer, Victor J Cee, Holly L Deak, et al.
ACS Medicinal Chemistry Letters
|
April 21, 2016
Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors
Victor J Cee, Frank Chavez, Bradley Herberich, et al.
Journal of Medicinal Chemistry
|
January 27, 2007
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor
Brian L Hodous, Stephanie D Geuns-Meyer, Paul E Hughes, et al.
ACS Medicinal Chemistry Letters
|
September 19, 2019
Discovery of <i>N</i>-(1-Acryloylazetidin-3-yl)-2-(1<i>H</i>-indol-1-yl)acetamides as Covalent Inhibitors of KRAS<sup>G12C</sup>
Youngsook Shin, Joon Won Jeong, Ryan P Wurz, et al.
Page
of 4