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ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1)
Brian A Lanman, Victor J Cee, Srinivasa R Cheruku, et al.
Journal of Medicinal Chemistry
|
June 11, 2016
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors
Liping H Pettus, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
January 10, 2019
Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies
Hui-Ling Wang, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
August 6, 2010
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor
Victor J Cee, Laurie B Schenkel, Brian L Hodous, et al.
Nature
|
November 1, 2019
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
Jude Canon, Karen Rex, Anne Y Saiki, et al.
Journal of Medicinal Chemistry
|
February 11, 2025
Identification of Structurally Novel KRAS<sup>G12C</sup> Inhibitors through Covalent DNA-Encoded Library Screening
David Huang, Francesco Manoni, Zhen Sun, et al.
Journal of Medicinal Chemistry
|
May 3, 2012
Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
August 18, 2012
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
September 15, 2006
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity
Erin F DiMauro, John Newcomb, Joseph J Nunes, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
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Search research articles
Search
Showing results (31-40 of 40) with videos related to
Sort By:
Page
of 4
You have reached the last page of results.
This site can display upto 40 results.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Discovery of a Potent, S1P3-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P1)
Brian A Lanman, Victor J Cee, Srinivasa R Cheruku, et al.
Journal of Medicinal Chemistry
|
June 11, 2016
Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors
Liping H Pettus, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
January 10, 2019
Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies
Hui-Ling Wang, Kristin L Andrews, Shon K Booker, et al.
Journal of Medicinal Chemistry
|
August 6, 2010
Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor
Victor J Cee, Laurie B Schenkel, Brian L Hodous, et al.
Nature
|
November 1, 2019
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
Jude Canon, Karen Rex, Anne Y Saiki, et al.
Journal of Medicinal Chemistry
|
February 11, 2025
Identification of Structurally Novel KRAS<sup>G12C</sup> Inhibitors through Covalent DNA-Encoded Library Screening
David Huang, Francesco Manoni, Zhen Sun, et al.
Journal of Medicinal Chemistry
|
May 3, 2012
Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
August 18, 2012
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
September 15, 2006
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity
Erin F DiMauro, John Newcomb, Joseph J Nunes, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
Page
of 4