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Science Advances|November 19, 2025
Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathwayYannis Hara, Viktor T Lemgart, Samuel Lessard, et al.Cell Stem Cell|May 4, 2019
Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous RecombinationRenata M Martin, Kazuya Ikeda, M Kyle Cromer, et al.Nature Medicine|January 30, 2019
Identification of preexisting adaptive immunity to Cas9 proteins in humansCarsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, et al.Nature Medicine|March 19, 2021
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cellsM Kyle Cromer, Joab Camarena, Renata M Martin, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|February 15, 2026
Reprogramming CD22 CAR-T cells in vivo Using CD8-Targeted mRNA-LNPs to Treat Hematological MalignanciesViktor T Lemgart, Andrew J Sawyer, William Kuhlman, et al.Pageof 1