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Journal of Molecular Biology|August 19, 2008
Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibodyBrian M Beyer, Richard Ingram, Lata Ramanathan, et al.Genome Biology|September 13, 2002
Human members of the eukaryotic protein kinase familyMitch Kostich, Jessie English, Vincent Madison, et al.Journal of Medicinal Chemistry|September 30, 2005
Design, synthesis, and biological activity of m-tyrosine-based 16- and 17-membered macrocyclic inhibitors of hepatitis C virus NS3 serine proteaseKevin X Chen, F George Njoroge, John Pichardo, et al.Journal of Medicinal Chemistry|January 20, 2006
Potent 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid-based macrocyclic inhibitors of hepatitis C virus NS3 proteaseKevin X Chen, F George Njoroge, John Pichardo, et al.Journal of Chemical Theory and Computation|December 3, 2015
Computational Study of the Effects of Mutations A156T, D168V, and D168Q on the Binding of HCV Protease InhibitorsZhuyan Guo, Andrew Prongay, Xiao Tong, et al.Bioorganic & Medicinal Chemistry Letters|December 5, 2008
Discovery of novel spirocyclopropyl hydroxamate and carboxylate compounds as TACE inhibitorsZhuyan Guo, Peter Orth, Shing-Chun Wong, et al.Journal of Medicinal Chemistry|February 6, 2008
Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors: Part I--discovery of two binding modesZhaoning Zhu, Robert Mazzola, Lisa Sinning, et al.Bioorganic & Medicinal Chemistry Letters|May 30, 2006
P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine proteaseAshok Arasappan, F George Njoroge, Kevin X Chen, et al.Protein Engineering, Design & Selection : PEDS|May 6, 2008
Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stabilityWenyan Wang, Winifred W Prosise, Jun Chen, et al.Biochemistry|February 1, 2006
Impact of naturally occurring variants of HCV protease on the binding of different classes of protease inhibitorsXiao Tong, Zhuyan Guo, Jacquelyn Wright-Minogue, et al.Pageof 4