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Journal of Medicinal Chemistry
|
January 23, 2004
Design, synthesis, and biological activity of 4-[(4-cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles as potent and selective farnesyltransferase inhibitors
Le Wang, Gary T Wang, Xilu Wang, et al.
Biochemistry
|
June 14, 2006
Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors
Kenton L Longenecker, Kent D Stewart, David J Madar, et al.
Chemical Biology & Drug Design
|
February 24, 2006
Structure-based optimization of MurF inhibitors
Geoffrey F Stamper, Kenton L Longenecker, Elizabeth H Fry, et al.
Journal of Computer-Aided Molecular Design
|
February 13, 2007
Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery
Kent D Stewart, Kevin Steffy, Kevin Harris, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 5, 2008
Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives
Douglas K Hutchinson, Teresa Rosenberg, Larry L Klein, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2006
Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity
Gui-Dong Zhu, Jianchun Gong, Akiyo Claiborne, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 13, 2006
Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation
Qun Li, Tongmei Li, Gui-Dong Zhu, et al.
Journal of Medicinal Chemistry
|
March 19, 2004
Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization
William J Sanders, Vicki L Nienaber, Claude G Lerner, et al.
Journal of Medicinal Chemistry
|
April 2, 2019
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer
Andrew M Petros, Alla Korepanova, Clarissa G Jakob, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 18, 2006
Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer
Qun Li, Keith W Woods, Sheela Thomas, et al.
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Search research articles
Search
Showing results (21-30 of 40) with videos related to
Sort By:
Page
of 4
Journal of Medicinal Chemistry
|
January 23, 2004
Design, synthesis, and biological activity of 4-[(4-cyano-2-arylbenzyloxy)-(3-methyl-3H-imidazol-4-yl)methyl]benzonitriles as potent and selective farnesyltransferase inhibitors
Le Wang, Gary T Wang, Xilu Wang, et al.
Biochemistry
|
June 14, 2006
Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors
Kenton L Longenecker, Kent D Stewart, David J Madar, et al.
Chemical Biology & Drug Design
|
February 24, 2006
Structure-based optimization of MurF inhibitors
Geoffrey F Stamper, Kenton L Longenecker, Elizabeth H Fry, et al.
Journal of Computer-Aided Molecular Design
|
February 13, 2007
Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery
Kent D Stewart, Kevin Steffy, Kevin Harris, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 5, 2008
Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives
Douglas K Hutchinson, Teresa Rosenberg, Larry L Klein, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 11, 2006
Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity
Gui-Dong Zhu, Jianchun Gong, Akiyo Claiborne, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 13, 2006
Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation
Qun Li, Tongmei Li, Gui-Dong Zhu, et al.
Journal of Medicinal Chemistry
|
March 19, 2004
Discovery of potent inhibitors of dihydroneopterin aldolase using CrystaLEAD high-throughput X-ray crystallographic screening and structure-directed lead optimization
William J Sanders, Vicki L Nienaber, Claude G Lerner, et al.
Journal of Medicinal Chemistry
|
April 2, 2019
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer
Andrew M Petros, Alla Korepanova, Clarissa G Jakob, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 18, 2006
Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer
Qun Li, Keith W Woods, Sheela Thomas, et al.
Page
of 4