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The Journal of Biological Chemistry|February 27, 2013
E6AP/UBE3A ubiquitin ligase harbors two E2~ubiquitin binding sitesVirginia P Ronchi, Jennifer M Klein, Arthur L Haas
The Journal of Biological Chemistry|November 26, 2013
The active form of E6-associated protein (E6AP)/UBE3A ubiquitin ligase is an oligomerVirginia P Ronchi, Jennifer M Klein, Daniel J Edwards, et al.
Methods in Molecular Biology (Clifton, N.J.)|February 22, 2012
Measuring rates of ubiquitin chain formation as a functional readout of ligase activityVirginia P Ronchi, Arthur L Haas
The Journal of Biological Chemistry|September 20, 2017
In silico modeling of the cryptic E2∼ubiquitin-binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assemblyVirginia P Ronchi, Elizabeth D Kim, Christopher M Summa, et al.
The Journal of Biological Chemistry|February 15, 2013
Tripartite motif ligases catalyze polyubiquitin chain formation through a cooperative allosteric mechanismFrederick C Streich, Virginia P Ronchi, J Patrick Connick, et al.
The Journal of Biological Chemistry|October 25, 2014
Convergent evolution in the assembly of polyubiquitin degradation signals by the Shigella flexneri IpaH9.8 ligaseDaniel J Edwards, Frederick C Streich, Virginia P Ronchi, et al.
The Journal of Biological Chemistry|November 3, 2010
Ser(120) of Ubc2/Rad6 regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1Brajesh Kumar, Kimberly G Lecompte, Jennifer M Klein, et al.
The Journal of Biological Chemistry|October 4, 2017
The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assemblyDustin R Todaro, Allison C Augustus-Wallace, Jennifer M Klein, et al.
The Journal of Biological Chemistry|October 6, 2018
Oligomerization of the HECT ubiquitin ligase NEDD4-2/NEDD4L is essential for polyubiquitin chain assemblyDustin R Todaro, Allison C Augustus-Wallace, Jennifer M Klein, et al.
The Journal of Biological Chemistry|November 10, 2011
E1-E2 interactions in ubiquitin and Nedd8 ligation pathwaysZeynep Tokgöz, Thomas J Siepmann, Frederick Streich, et al.
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