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Journal of the American Heart Association|February 8, 2025
Melanocortin 1 Receptor Regulates Pathological and Physiological Cardiac RemodelingAnni Suominen, Aino Suni, Saku Ruohonen, et al.
Journal of Chemical Information and Modeling|September 11, 2020
Rigorous Computational Study Reveals What Docking Overlooks: Double Trouble from Membrane Association in Protein Kinase C ModulatorsSaara Lautala, Riccardo Provenzani, Artturi Koivuniemi, et al.
ACS Medicinal Chemistry Letters|May 22, 2020
Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential ChemotherapeuticsIlari Tarvainen, Tomáš Zimmermann, Pia Heinonen, et al.
Journal of Medicinal Chemistry|September 1, 2017
Discovery of Small Molecules Targeting the Synergy of Cardiac Transcription Factors GATA4 and NKX2-5Mika J Välimäki, Marja A Tölli, Sini M Kinnunen, et al.
Scientific Reports|April 18, 2024
Affinity chromatography reveals direct binding of the GATA4-NKX2-5 interaction inhibitor (3i-1000) with GATA4Mikael Jumppanen, Sini M Kinnunen, Matej Zore, et al.
The Journal of Physiology|November 11, 2021
Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell-derived cardiomyocytesEline Huethorst, Peter Mortensen, Radostin D Simitev, et al.
Materials Today. Bio|September 22, 2025
Melt electrowritten medium chain length polyhydroxyalkanoate cardiac patches for Post-MI cardiac regenerationQasim A Majid, Pragati Pandey, Mohamed Bellahcene, et al.
Plos One|April 12, 2018
Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase CRiccardo Provenzani, Ilari Tarvainen, Giulia Brandoli, et al.
Pharmacological Research|May 7, 2013
The C1 domain-targeted isophthalate derivative HMI-1b11 promotes neurite outgrowth and GAP-43 expression through PKCα activation in SH-SY5Y cellsVirpi Talman, Marialaura Amadio, Cecilia Osera, et al.
Journal of Medicinal Chemistry|August 22, 2019
Synthesis, Identification, and Structure-Activity Relationship Analysis of GATA4 and NKX2-5 Protein-Protein Interaction ModulatorsMikael Jumppanen, Sini M Kinnunen, Mika J Välimäki, et al.
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