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The EMBO Journal|April 16, 2024
Non-vesicular phosphatidylinositol transfer plays critical roles in defining organelle lipid compositionYeun Ju Kim, Joshua G Pemberton, Andrea Eisenreichova, et al.European Journal of Medicinal Chemistry|August 11, 2023
Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapyMilan Dejmek, Andrea Brazdova, Tomáš Otava, et al.Nucleic Acids Research|April 14, 2022
Guanine quadruplexes in the RNA genome of the tick-borne encephalitis virus: their role as a new antiviral target and in virus biologyJiří Holoubek, Klára Bednářová, Jan Haviernik, et al.Biochemistry|November 17, 2021
Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity CorrelationsBarbora Novotná, Lucie Holá, Monika Staś, et al.The Journal of Cell Biology|February 24, 2018
PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sitesMira Sohn, Marek Korzeniowski, James P Zewe, et al.Protein Science : a Publication of the Protein Society|August 30, 2022
Crystal structure of SARS-CoV-2 nsp10-nsp16 in complex with small molecule inhibitors, SS148 and WZ16Martin Klima, Aliakbar Khalili Yazdi, Fengling Li, et al.Scientific Reports|March 25, 2016
Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 proteinMartin Klima, Dániel J Tóth, Rozalie Hexnerova, et al.Journal of Lipid Research|January 11, 2019
A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alphaNivedita Sengupta, Marko Jović, Elena Barnaeva, et al.Journal of Medicinal Chemistry|October 6, 2022
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor AgonistsZdeněk Vavřina, Pavla Perlíková, Nemanja Milisavljević, et al.Bioorganic & Medicinal Chemistry|December 2, 2014
Norbornane-based nucleoside and nucleotide analogues locked in North conformationMilan Dejmek, Michal Šála, Hubert Hřebabecký, et al.Pageof 12