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Proceedings of the National Academy of Sciences of the United States of America|January 27, 2019
Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interactionRoman C Hillig, Brice Sautier, Jens Schroeder, et al.Journal of Medicinal Chemistry|October 25, 2024
Discovery and Characterization of BAY-184: A New Potent and Selective Acylsulfonamide-Benzofuran In Vivo-Active KAT6AB InhibitorAntonius Ter Laak, Roman C Hillig, Steven J Ferrara, et al.SLAS Discovery : Advancing Life Sciences R & D|June 22, 2021
Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput ScreeningStefan Gradl, Holger Steuber, Joerg Weiske, et al.Nature Chemical Biology|May 24, 2016
Structural analysis of human KDM5B guides histone demethylase inhibitor developmentCatrine Johansson, Srikannathasan Velupillai, Anthony Tumber, et al.Journal of Medicinal Chemistry|April 15, 2016
Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (BAY-598) for the Protein Lysine Methyltransferase SMYD2Erik Eggert, Roman C Hillig, Silke Koehr, et al.Nature Chemical Biology|April 2, 2020
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophilesJohn K Eaton, Laura Furst, Richard A Ruberto, et al.ACS Chemical Biology|October 19, 2017
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of ActionAmaury E Fernández-Montalván, Markus Berger, Benno Kuropka, et al.Pageof 2