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Bioorganic & Medicinal Chemistry|April 1, 1995
Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3W C Groutas, M J Brubaker, L S Chong, et al.Biochimica Et Biophysica Acta|August 7, 1993
3-(Alkylthio)-N-hydroxysuccinimide derivatives: potent inhibitors of human leukocyte elastaseW C Groutas, R Venkataraman, M J Brubaker, et al.Bioorganic & Medicinal Chemistry|July 6, 2000
Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylatesR Kuang, J B Epp, S Ruan, et al.Journal of Medicinal Chemistry|June 1, 1982
Synthesis, X-ray crystallographic determination, and opioid activity of erythro-5-methylmethadone enantiomers. Evidence which suggests that mu and delta opioid receptors possess different stereochemical requirementsP S Portoghese, J H Poupaert, D L Larson, et al.Biochemical and Biophysical Research Communications|August 16, 1993
Mechanism-based inhibitors of serine proteinases based on the Gabriel-Colman rearrangementW C Groutas, L S Chong, R Venkataraman, et al.Journal of Medicinal Chemistry|July 1, 1986
Inactivation of leukocyte elastase by aryl azolides and sulfonate salts. Structure-activity relationship studiesW C Groutas, M J Brubaker, M E Zandler, et al.Drug Design and Discovery|February 1, 1994
Derivatives of 3-alkyl-N-hydroxysuccinimide: probing the effect of structure on bioactivity toward human leukocyte elastaseW C Groutas, M J Brubaker, L S Chong, et al.Journal of Medicinal Chemistry|February 1, 1985
Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastaseW C Groutas, W R Abrams, M C Theodorakis, et al.Archives of Biochemistry and Biophysics|May 22, 2001
1,2,5-Thiadiazolidin-3-one 1,1 dioxide: a powerful scaffold for probing the S' subsites of (chymo)trypsin-like serine proteasesW C Groutas, J B Epp, R Kuang, et al.Pageof 4