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Current Opinion in Chemical Biology
|
July 27, 2001
SH2 domain inhibition: a problem solved?
W C Shakespeare
Current Opinion in Drug Discovery & Development
|
August 4, 2009
Signal transduction drug discovery: targets, mechanisms and structure-based design
D C Dalgarno, C A Metcalf, W C Shakespeare, et al.
Chemistry & Biology
|
November 18, 1998
A novel mechanism-based mammalian cell assay for the identification of SH2-domain-specific protein-protein inhibitors
R J Rickles, P A Henry, W Guan, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
|
July 1, 1996
ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats
Z G Zhang, D Reif, J Macdonald, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 1999
An efficient synthesis of a 4'-phosphonodifluoromethyl-3'-formyl-phenylalanine containing SRC SH2 ligand
W C Shakespeare, R S Bohacek, S S Narula, et al.
Chemistry & Biology
|
March 14, 2000
A Src SH2 selective binding compound inhibits osteoclast-mediated resorption
S M Violette, W C Shakespeare, C Bartlett, et al.
Journal of Medicinal Chemistry
|
October 29, 2000
Structure-based design of novel bicyclic nonpeptide inhibitors for the src SH2 domain
W C Shakespeare, R S Bohacek, M D Azimioara, et al.
British Journal of Cancer
|
May 11, 2006
Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases
D P Lesslie, J M Summy, N U Parikh, et al.
Journal of Medicinal Chemistry
|
May 23, 1998
Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis
R Hirschmann, J Hynes, M A Cichy-Knight, et al.
Journal of Medicinal Chemistry
|
March 23, 2001
X-Ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor
R S Bohacek, D C Dalgarno, M Hatada, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
Current Opinion in Chemical Biology
|
July 27, 2001
SH2 domain inhibition: a problem solved?
W C Shakespeare
Current Opinion in Drug Discovery & Development
|
August 4, 2009
Signal transduction drug discovery: targets, mechanisms and structure-based design
D C Dalgarno, C A Metcalf, W C Shakespeare, et al.
Chemistry & Biology
|
November 18, 1998
A novel mechanism-based mammalian cell assay for the identification of SH2-domain-specific protein-protein inhibitors
R J Rickles, P A Henry, W Guan, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
|
July 1, 1996
ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats
Z G Zhang, D Reif, J Macdonald, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 24, 1999
An efficient synthesis of a 4'-phosphonodifluoromethyl-3'-formyl-phenylalanine containing SRC SH2 ligand
W C Shakespeare, R S Bohacek, S S Narula, et al.
Chemistry & Biology
|
March 14, 2000
A Src SH2 selective binding compound inhibits osteoclast-mediated resorption
S M Violette, W C Shakespeare, C Bartlett, et al.
Journal of Medicinal Chemistry
|
October 29, 2000
Structure-based design of novel bicyclic nonpeptide inhibitors for the src SH2 domain
W C Shakespeare, R S Bohacek, M D Azimioara, et al.
British Journal of Cancer
|
May 11, 2006
Vascular endothelial growth factor receptor-1 mediates migration of human colorectal carcinoma cells by activation of Src family kinases
D P Lesslie, J M Summy, N U Parikh, et al.
Journal of Medicinal Chemistry
|
May 23, 1998
Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis
R Hirschmann, J Hynes, M A Cichy-Knight, et al.
Journal of Medicinal Chemistry
|
March 23, 2001
X-Ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor
R S Bohacek, D C Dalgarno, M Hatada, et al.
Page
of 2