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Lipids|September 5, 2008
CYP51: A major drug target in the cytochrome P450 superfamilyGalina I Lepesheva, Tatyana Y Hargrove, Yuliya Kleshchenko, et al.
Archives of Biochemistry and Biophysics|November 19, 2008
Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformansW David Nes, Wenxu Zhou, Kulothungan Ganapathy, et al.
The Biochemical Journal|August 30, 2013
C-24-methylation of 26-fluorocycloartenols by recombinant sterol C-24-methyltransferase from soybean: evidence for channel switching and its phylogenetic implicationsPresheet Patkar, Brad A Haubrich, Ming Qi, et al.
Journal of Medicinal Chemistry|November 29, 2021
Relaxed Substrate Requirements of Sterol 14α-Demethylase from <i>Naegleria fowleri</i> Are Accompanied by Resistance to InhibitionTatiana Y Hargrove, Zdzislaw Wawrzak, Girish Rachakonda, et al.
Chemistry & Biology|October 27, 2015
Fluorinated Sterols Are Suicide Inhibitors of Ergosterol Biosynthesis and Growth in Trypanosoma bruceiDavid J Leaver, Presheet Patkar, Ujjal K Singha, et al.
Antimicrobial Agents and Chemotherapy|October 14, 2015
In Vitro Biochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatusAndrew G S Warrilow, Josie E Parker, Claire L Price, et al.
Plos Pathogens|September 14, 2018
Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleriWenxu Zhou, Anjan Debnath, Gareth Jennings, et al.
Archives of Biochemistry and Biophysics|March 27, 2012
Sterol C24-methyltransferase: Physio- and stereo-chemical features of the sterol C3 group required for catalytic competenceAlicia L Howard, Jialin Liu, Gamal A Elmegeed, et al.
Biochemistry|January 14, 2004
Sterol methyltransferase: functional analysis of highly conserved residues by site-directed mutagenesisW David Nes, Pruthvi Jayasimha, Wenxu Zhou, et al.
Journal of Lipid Research|October 19, 2017
Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug designMedhanie E Kidane, Boden H Vanderloop, Wenxu Zhou, et al.
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