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Journal of Medicinal Chemistry
|
December 12, 2024
Discovery of VU6024578/BI02982816: An mGlu<sub>1</sub> Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, et al.
ACS Pharmacology & Translational Science
|
August 23, 2021
Discovery of the First Selective M<sub>4</sub> Muscarinic Acetylcholine Receptor Antagonists with <i>in Vivo</i> Antiparkinsonian and Antidystonic Efficacy
Mark S Moehle, Aaron M Bender, Jonathan W Dickerson, et al.
Journal of Medicinal Chemistry
|
October 17, 2025
Optimization of Selective and CNS Penetrant Alkyne-Based TREK Inhibitors: The Discovery and Characterization of ONO-9517601 (VU6022856) and ONO-7927846 (VU6024391)
Motoyuki Tanaka, Yoko Sekioka, Gakuji Hashimoto, et al.
ACS Chemical Neuroscience
|
January 25, 2026
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust <i>In Vivo</i> Efficacy
Alison R Gregro, Charlotte Park, Madeline F Long, et al.
ACS Chemical Neuroscience
|
December 11, 2024
Discovery of VU0467319: an M<sub>1</sub> Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
Michael S Poslunsey, Michael R Wood, Changho Han, et al.
Genome Biology
|
October 19, 2011
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control
Robert S Coyne, Linda Hannick, Dhanasekaran Shanmugam, et al.
ACS Chemical Neuroscience
|
June 6, 2026
Discovery of VU6053371/BI03738809: A First-in-Class Selective and CNS-Penetrant mGlu<sub>3</sub> Positive Allosteric Modulator (PAM) with Efficacy in a Preclinical Cognition Model
Caleb A Jones, Renn A Duncan, Kristen M Gilliland, et al.
Journal of Water and Health
|
October 7, 2011
Daily measures of microbes and human health at a non-point source marine beach
Amir M Abdelzaher, Mary E Wright, Cristina Ortega, et al.
Neuron
|
May 5, 2015
Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents
Jerri M Rook, Zixiu Xiang, Xiaohui Lv, et al.
Micropublication Biology
|
March 3, 2025
The <i>M.3.2</i> mutation in <i>Drosophila melanogaster</i> mapped as a novel allele of <i>tout-velu</i>
MacKenzie Patterson, Adriana R Andrus, Conner Bell, et al.
Page
of 30
Search research articles
Search
Showing results (291-300 of 300) with videos related to
Sort By:
Page
of 30
You have reached the last page of results.
This site can display upto 300 results.
Journal of Medicinal Chemistry
|
December 12, 2024
Discovery of VU6024578/BI02982816: An mGlu<sub>1</sub> Positive Allosteric Modulator with Efficacy in Preclinical Antipsychotic and Cognition Models
Carson W Reed, Jacob F Kalbfleisch, Jeremy A Turkett, et al.
ACS Pharmacology & Translational Science
|
August 23, 2021
Discovery of the First Selective M<sub>4</sub> Muscarinic Acetylcholine Receptor Antagonists with <i>in Vivo</i> Antiparkinsonian and Antidystonic Efficacy
Mark S Moehle, Aaron M Bender, Jonathan W Dickerson, et al.
Journal of Medicinal Chemistry
|
October 17, 2025
Optimization of Selective and CNS Penetrant Alkyne-Based TREK Inhibitors: The Discovery and Characterization of ONO-9517601 (VU6022856) and ONO-7927846 (VU6024391)
Motoyuki Tanaka, Yoko Sekioka, Gakuji Hashimoto, et al.
ACS Chemical Neuroscience
|
January 25, 2026
Discovery of VU6025733 (AG06827): A Highly Selective, Orally Bioavailable, and Structurally Distinct M<sub>4</sub> Muscarinic Acetylcholine Receptor Positive Allosteric Modulator (PAM) with Robust <i>In Vivo</i> Efficacy
Alison R Gregro, Charlotte Park, Madeline F Long, et al.
ACS Chemical Neuroscience
|
December 11, 2024
Discovery of VU0467319: an M<sub>1</sub> Positive Allosteric Modulator Candidate That Advanced into Clinical Trials
Michael S Poslunsey, Michael R Wood, Changho Han, et al.
Genome Biology
|
October 19, 2011
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control
Robert S Coyne, Linda Hannick, Dhanasekaran Shanmugam, et al.
ACS Chemical Neuroscience
|
June 6, 2026
Discovery of VU6053371/BI03738809: A First-in-Class Selective and CNS-Penetrant mGlu<sub>3</sub> Positive Allosteric Modulator (PAM) with Efficacy in a Preclinical Cognition Model
Caleb A Jones, Renn A Duncan, Kristen M Gilliland, et al.
Journal of Water and Health
|
October 7, 2011
Daily measures of microbes and human health at a non-point source marine beach
Amir M Abdelzaher, Mary E Wright, Cristina Ortega, et al.
Neuron
|
May 5, 2015
Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents
Jerri M Rook, Zixiu Xiang, Xiaohui Lv, et al.
Micropublication Biology
|
March 3, 2025
The <i>M.3.2</i> mutation in <i>Drosophila melanogaster</i> mapped as a novel allele of <i>tout-velu</i>
MacKenzie Patterson, Adriana R Andrus, Conner Bell, et al.
Page
of 30