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Bioorganic & Medicinal Chemistry Letters
|
September 21, 2017
Discovery of highly potent, selective, covalent inhibitors of JAK3
James Kempson, Damaso Ovalle, Junqing Guo, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 27, 2020
Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists
Lalgudi S Harikrishnan, Patrice Gill, Muthoni G Kamau, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 2, 2019
Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists
Zhonghui Lu, James J-W Duan, Haiyun Xiao, et al.
ACS Medicinal Chemistry Letters
|
March 21, 2019
Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists
James J-W Duan, Zhonghui Lu, Bin Jiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 26, 2017
Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors
John Hynes, Hong Wu, James Kempson, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 3, 2014
Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors
James J-W Duan, Zhonghui Lu, Bin Jiang, et al.
Anaesthesia
|
June 4, 2023
Postoperative pulmonary complications in older patients undergoing elective surgery with a supraglottic airway device or tracheal intubation
L Q Yang, L Zhu, X Shi, et al.
Journal of Medicinal Chemistry
|
December 2, 2020
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches
Hai-Yun Xiao, Ning Li, James J-W Duan, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Hua Gong, David S Weinstein, Zhonghui Lu, et al.
Page
of 24
Search research articles
Search
Showing results (191-200 of 235) with videos related to
Sort By:
Page
of 24
Bioorganic & Medicinal Chemistry Letters
|
September 21, 2017
Discovery of highly potent, selective, covalent inhibitors of JAK3
James Kempson, Damaso Ovalle, Junqing Guo, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 27, 2020
Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists
Lalgudi S Harikrishnan, Patrice Gill, Muthoni G Kamau, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 2, 2019
Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists
Zhonghui Lu, James J-W Duan, Haiyun Xiao, et al.
ACS Medicinal Chemistry Letters
|
March 21, 2019
Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists
James J-W Duan, Zhonghui Lu, Bin Jiang, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 26, 2017
Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors
John Hynes, Hong Wu, James Kempson, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 3, 2014
Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors
James J-W Duan, Zhonghui Lu, Bin Jiang, et al.
Anaesthesia
|
June 4, 2023
Postoperative pulmonary complications in older patients undergoing elective surgery with a supraglottic airway device or tracheal intubation
L Q Yang, L Zhu, X Shi, et al.
Journal of Medicinal Chemistry
|
December 2, 2020
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches
Hai-Yun Xiao, Ning Li, James J-W Duan, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
Robert J Cherney, Lyndon A M Cornelius, Anurag Srivastava, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 14, 2017
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Hua Gong, David S Weinstein, Zhonghui Lu, et al.
Page
of 24