W F Trager - JoVE Visualize

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Molecular Pharmacology|August 1, 1987

Inactivation of multiple hepatic cytochrome P-450 isozymes in rats by allylisopropylacetamide: mechanistic implicationsL M Bornheim, M C Underwood, P Caldera, et al.

Archives of Biochemistry and Biophysics|November 1, 1987

Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adductsM A Correia, C Decker, K Sugiyama, et al.

Steroids|February 1, 1980

Carbon-13 nuclear magnetic resonance studies of spironolactone and several related steroidsR J Highet, T R Burke, W F Trager, et al.

Clinical Pharmacology and Therapeutics|April 1, 1992

The mechanism of the interaction between amiodarone and warfarin in humansL D Heimark, L Wienkers, K Kunze, et al.

Biochemistry|March 17, 1999

Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin bindingR L Haining, J P Jones, K R Henne, et al.

Journal of Clinical Pharmacology|March 20, 1998

Lack of effect of azelastine and ketoconazole coadministration on electrocardiographic parameters in healthy volunteersJ Morganroth, W H Lyness, J L Perhach, et al.

Clinical Pharmacology and Therapeutics|September 1, 1993

Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosisT A O'Sullivan, J P Wang, J D Unadkat, et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 1, 1993

Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species differenceT F Woolf, W F Pool, S M Bjorge, et al.

Chemical Research in Toxicology|January 1, 1992

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactionsA E Rettie, K R Korzekwa, K L Kunze, et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 1, 1996

Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studiesD J Black, K L Kunze, L C Wienkers, et al.

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Showing results (71-80 of 85) with videos related to

Sort By:

Pageof 9

Molecular Pharmacology|August 1, 1987

Inactivation of multiple hepatic cytochrome P-450 isozymes in rats by allylisopropylacetamide: mechanistic implicationsL M Bornheim, M C Underwood, P Caldera, et al.

Archives of Biochemistry and Biophysics|November 1, 1987

Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adductsM A Correia, C Decker, K Sugiyama, et al.

Steroids|February 1, 1980

Carbon-13 nuclear magnetic resonance studies of spironolactone and several related steroidsR J Highet, T R Burke, W F Trager, et al.

Clinical Pharmacology and Therapeutics|April 1, 1992

The mechanism of the interaction between amiodarone and warfarin in humansL D Heimark, L Wienkers, K Kunze, et al.

Biochemistry|March 17, 1999

Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin bindingR L Haining, J P Jones, K R Henne, et al.

Journal of Clinical Pharmacology|March 20, 1998

Lack of effect of azelastine and ketoconazole coadministration on electrocardiographic parameters in healthy volunteersJ Morganroth, W H Lyness, J L Perhach, et al.

Clinical Pharmacology and Therapeutics|September 1, 1993

Disposition of drugs in cystic fibrosis. V. In vivo CYP2C9 activity as probed by (S)-warfarin is not enhanced in cystic fibrosisT A O'Sullivan, J P Wang, J D Unadkat, et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 1, 1993

Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species differenceT F Woolf, W F Pool, S M Bjorge, et al.

Chemical Research in Toxicology|January 1, 1992

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactionsA E Rettie, K R Korzekwa, K L Kunze, et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 1, 1996

Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studiesD J Black, K L Kunze, L C Wienkers, et al.

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