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ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

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JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

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W J Howe

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Journal of Medicinal Chemistry|September 30, 1994

Structure-based design of HIV protease inhibitors: 4-hydroxycoumarins and 4-hydroxy-2-pyrones as non-peptidic inhibitorsS Thaisrivongs, P K Tomich, K D Watenpaugh, et al.

The Journal of Biological Chemistry|August 25, 1990

Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2A G Tomasselli, J O Hui, T K Sawyer, et al.

Journal of Medicinal Chemistry|April 16, 1993

Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostereS Thaisrivongs, S R Turner, J W Strohbach, et al.

Biochemistry|August 16, 1994

The HIV-1 protease as enzyme and substrate: mutagenesis of autolysis sites and generation of a stable mutant with retained kinetic propertiesA M Mildner, D J Rothrock, J W Leone, et al.

Journal of Medicinal Chemistry|October 27, 1995

Structure-based design of nonpeptidic HIV protease inhibitors from a cyclooctylpyranone lead structureK R Romines, K D Watenpaugh, W J Howe, et al.

Journal of Medicinal Chemistry|December 22, 1995

Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitorsH I Skulnick, P D Johnson, W J Howe, et al.

Journal of Medicinal Chemistry|May 26, 1995

Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitorsK R Romines, K D Watenpaugh, P K Tomich, et al.

Journal of Medicinal Chemistry|September 27, 1996

Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationshipsK R Romines, J K Morris, W J Howe, et al.

Journal of Medicinal Chemistry|November 8, 1996

Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitorsS Thaisrivongs, D L Romero, R A Tommasi, et al.

Journal of Medicinal Chemistry|October 25, 1996

Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitorsS Thaisrivongs, H I Skulnick, S R Turner, et al.

Pageof 3

Search research articles

Showing results (11-20 of 21) with videos related to

Sort By:

Pageof 3

Journal of Medicinal Chemistry|September 30, 1994

Structure-based design of HIV protease inhibitors: 4-hydroxycoumarins and 4-hydroxy-2-pyrones as non-peptidic inhibitorsS Thaisrivongs, P K Tomich, K D Watenpaugh, et al.

The Journal of Biological Chemistry|August 25, 1990

Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2A G Tomasselli, J O Hui, T K Sawyer, et al.

Journal of Medicinal Chemistry|April 16, 1993

Biochemistry|August 16, 1994

The HIV-1 protease as enzyme and substrate: mutagenesis of autolysis sites and generation of a stable mutant with retained kinetic propertiesA M Mildner, D J Rothrock, J W Leone, et al.

Journal of Medicinal Chemistry|October 27, 1995

Structure-based design of nonpeptidic HIV protease inhibitors from a cyclooctylpyranone lead structureK R Romines, K D Watenpaugh, W J Howe, et al.

Journal of Medicinal Chemistry|December 22, 1995

Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitorsH I Skulnick, P D Johnson, W J Howe, et al.

Journal of Medicinal Chemistry|May 26, 1995

Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitorsK R Romines, K D Watenpaugh, P K Tomich, et al.

Journal of Medicinal Chemistry|September 27, 1996

Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationshipsK R Romines, J K Morris, W J Howe, et al.

Journal of Medicinal Chemistry|November 8, 1996

Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitorsS Thaisrivongs, D L Romero, R A Tommasi, et al.

Journal of Medicinal Chemistry|October 25, 1996

Structure-based design of HIV protease inhibitors: sulfonamide-containing 5,6-dihydro-4-hydroxy-2-pyrones as non-peptidic inhibitorsS Thaisrivongs, H I Skulnick, S R Turner, et al.

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