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W Lindsley

Showing results (171-180 of 570) with videos related to

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Bioorganic & Medicinal Chemistry Letters|October 26, 2016
Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazolesKayla J Temple, Matthew T Duvernay, Jae G Maeng, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 13, 2015
A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L Blobaum, Frank W Byers, Thomas M Bridges, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry|March 19, 2015
Effects of VU0410120, a novel GlyT1 inhibitor, on measures of sociability, cognition and stereotypic behaviors in a mouse model of autismJessica A Burket, Andrew D Benson, Torrian L Green, et al.
Bioorganic & Medicinal Chemistry Letters|December 17, 2022
Persistent challenges in the development of an mGlu<sub>7</sub> PAM in vivo tool compound: The discovery of VU6046980Jacob J Kalbfleisch, Alice L Rodriguez, Xia Lei, et al.
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology|December 12, 2022
Efficacy of tezepelumab in patients with evidence of severe allergic asthma: Results from the phase 3 NAVIGATOR studyJonathan Corren, Christopher S Ambrose, Janet M Griffiths, et al.
British Journal of Pharmacology|May 4, 2021
Muscarinic M<sub>4</sub> and M<sub>5</sub> receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol-preferring ratsLeigh C Walker, Kate L Huckstep, Nicola A Chen, et al.
Immunity, Inflammation and Disease|September 14, 2016
Intratracheal myriocin enhances allergen-induced Th2 inflammation and airway hyper-responsivenessRamakrishna Edukulla, Kira Lee Rehn, Bo Liu, et al.
Bioorganic & Medicinal Chemistry Letters|December 25, 2010
Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonistsJeffrey P Lamb, Darren W Engers, Colleen M Niswender, et al.
Bioorganic & Medicinal Chemistry Letters|October 28, 2011
Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: unexpected 'molecular switch' from a closely related mGlu4 positive allosteric modulatorThomas Utley, Dustin Haddenham, James M Salovich, et al.
Bioorganic & Medicinal Chemistry Letters|February 17, 2010
Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAMThomas M Bridges, J Phillip Kennedy, Meredith J Noetzel, et al.
Pageof 57

Showing results (171-180 of 570) with videos related to

Sort By:
Pageof 57
Bioorganic & Medicinal Chemistry Letters|October 26, 2016
Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazolesKayla J Temple, Matthew T Duvernay, Jae G Maeng, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 13, 2015
A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L Blobaum, Frank W Byers, Thomas M Bridges, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry|March 19, 2015
Effects of VU0410120, a novel GlyT1 inhibitor, on measures of sociability, cognition and stereotypic behaviors in a mouse model of autismJessica A Burket, Andrew D Benson, Torrian L Green, et al.
Bioorganic & Medicinal Chemistry Letters|December 17, 2022
Persistent challenges in the development of an mGlu<sub>7</sub> PAM in vivo tool compound: The discovery of VU6046980Jacob J Kalbfleisch, Alice L Rodriguez, Xia Lei, et al.
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology|December 12, 2022
Efficacy of tezepelumab in patients with evidence of severe allergic asthma: Results from the phase 3 NAVIGATOR studyJonathan Corren, Christopher S Ambrose, Janet M Griffiths, et al.
British Journal of Pharmacology|May 4, 2021
Muscarinic M<sub>4</sub> and M<sub>5</sub> receptors in the ventral subiculum differentially modulate alcohol seeking versus consumption in male alcohol-preferring ratsLeigh C Walker, Kate L Huckstep, Nicola A Chen, et al.
Immunity, Inflammation and Disease|September 14, 2016
Intratracheal myriocin enhances allergen-induced Th2 inflammation and airway hyper-responsivenessRamakrishna Edukulla, Kira Lee Rehn, Bo Liu, et al.
Bioorganic & Medicinal Chemistry Letters|December 25, 2010
Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonistsJeffrey P Lamb, Darren W Engers, Colleen M Niswender, et al.
Bioorganic & Medicinal Chemistry Letters|October 28, 2011
Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: unexpected 'molecular switch' from a closely related mGlu4 positive allosteric modulatorThomas Utley, Dustin Haddenham, James M Salovich, et al.
Bioorganic & Medicinal Chemistry Letters|February 17, 2010
Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAMThomas M Bridges, J Phillip Kennedy, Meredith J Noetzel, et al.
Pageof 57