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W Lindsley

Showing results (201-210 of 570) with videos related to

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Bioorganic & Medicinal Chemistry Letters|July 31, 2009
Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Richard Williams, Kari A Johnson, Patrick R Gentry, et al.
Bioorganic & Medicinal Chemistry Letters|August 10, 2016
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypesAlexander R Geanes, Hykeyung P Cho, Kellie D Nance, et al.
ACS Pharmacology & Translational Science|July 2, 2019
mGlu<sub>5</sub> Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu<sub>5</sub>-Endocannabinoid SignalingZixiu Xiang, Xiaohui Lv, James Maksymetz, et al.
Bioorganic & Medicinal Chemistry Letters|May 7, 2020
Synthesis and pharmacological evaluation of bivalent tethered ligands to target the mGlu<sub>2/4</sub> heterodimeric receptor results in a compound with mGlu<sub>2/2</sub> homodimer selectivityMark G Fulton, Matthew T Loch, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|October 27, 2009
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu5Andrew S Felts, Sam A Saleh, Uyen Le, et al.
Molecular Pharmacology|February 28, 2013
Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacologyKaren J Gregory, Elizabeth D Nguyen, Sean D Reiff, et al.
Bioorganic & Medicinal Chemistry Letters|March 25, 2015
Synthesis and structure-activity relationships of a series of 4-methoxy-3-(piperidin-4-yl)oxy benzamides as novel inhibitors of the presynaptic choline transporterSean R Bollinger, Darren W Engers, Elizabeth A Ennis, et al.
Journal of Medicinal Chemistry|March 15, 2011
Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2Scott E Wolkenberg, Zhijian Zhao, Catherine Thut, et al.
Plos Pathogens|May 29, 2015
Phospholipase D1 Couples CD4+ T Cell Activation to c-Myc-Dependent Deoxyribonucleotide Pool Expansion and HIV-1 ReplicationHarry E Taylor, Glenn E Simmons, Thomas P Mathews, et al.
Biochemical Pharmacology|May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptorElham Khajehali, Celine Valant, Manuela Jörg, et al.
Pageof 57

Showing results (201-210 of 570) with videos related to

Sort By:
Pageof 57
Bioorganic & Medicinal Chemistry Letters|July 31, 2009
Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Richard Williams, Kari A Johnson, Patrick R Gentry, et al.
Bioorganic & Medicinal Chemistry Letters|August 10, 2016
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypesAlexander R Geanes, Hykeyung P Cho, Kellie D Nance, et al.
ACS Pharmacology & Translational Science|July 2, 2019
mGlu<sub>5</sub> Positive Allosteric Modulators Facilitate Long-Term Potentiation via Disinhibition Mediated by mGlu<sub>5</sub>-Endocannabinoid SignalingZixiu Xiang, Xiaohui Lv, James Maksymetz, et al.
Bioorganic & Medicinal Chemistry Letters|May 7, 2020
Synthesis and pharmacological evaluation of bivalent tethered ligands to target the mGlu<sub>2/4</sub> heterodimeric receptor results in a compound with mGlu<sub>2/2</sub> homodimer selectivityMark G Fulton, Matthew T Loch, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters|October 27, 2009
Discovery and SAR of 6-substituted-4-anilinoquinazolines as non-competitive antagonists of mGlu5Andrew S Felts, Sam A Saleh, Uyen Le, et al.
Molecular Pharmacology|February 28, 2013
Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacologyKaren J Gregory, Elizabeth D Nguyen, Sean D Reiff, et al.
Bioorganic & Medicinal Chemistry Letters|March 25, 2015
Synthesis and structure-activity relationships of a series of 4-methoxy-3-(piperidin-4-yl)oxy benzamides as novel inhibitors of the presynaptic choline transporterSean R Bollinger, Darren W Engers, Elizabeth A Ennis, et al.
Journal of Medicinal Chemistry|March 15, 2011
Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2Scott E Wolkenberg, Zhijian Zhao, Catherine Thut, et al.
Plos Pathogens|May 29, 2015
Phospholipase D1 Couples CD4+ T Cell Activation to c-Myc-Dependent Deoxyribonucleotide Pool Expansion and HIV-1 ReplicationHarry E Taylor, Glenn E Simmons, Thomas P Mathews, et al.
Biochemical Pharmacology|May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptorElham Khajehali, Celine Valant, Manuela Jörg, et al.
Pageof 57