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Cell Reports
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November 3, 2021
mGlu<sub>1</sub> potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits
James Maksymetz, Nellie E Byun, Deborah J Luessen, et al.
Frontiers in Pharmacology
|
January 26, 2012
Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1
Rene Raphemot, Daniel F Lonergan, Thuy T Nguyen, et al.
The Journal of Biological Chemistry
|
July 29, 2014
Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition
Thomas H Oguin, Shalini Sharma, Amanda D Stuart, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 30, 2020
Lead optimization of the VU0486321 series of mGlu<sub>1</sub> PAMs. Part 4: SAR reveals positive cooperativity across multiple mGlu receptor subtypes leading to subtype unselective PAMs
Dexter C Davis, Joseph D Bungard, Sichen Chang, et al.
Prostaglandins & Other Lipid Mediators
|
July 6, 2019
The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity
Ryan P Ceddia, Jason D Downey, Ryan D Morrison, et al.
Journal of Medicinal Chemistry
|
June 13, 2018
Sterol 14α-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis
Laura Friggeri, Tatiana Y Hargrove, Zdzislaw Wawrzak, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 11, 2019
Towards a TREK-1/2 (TWIK-Related K+ Channel 1 and 2) dual activator tool compound: Multi-dimensional optimization of BL-1249
Yuzo Iwaki, Kentaro Yashiro, Masaya Kokubo, et al.
ACS Chemical Neuroscience
|
April 24, 2010
Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening
Ralf Mueller, Alice L Rodriguez, Eric S Dawson, et al.
Journal of Medicinal Chemistry
|
August 3, 2016
Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1H-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with in Vivo Utility and Activity Against γ-Thrombin
Kayla J Temple, Matthew T Duvernay, Summer E Young, et al.
Journal of Cell Science
|
May 26, 2011
PLD1 rather than PLD2 regulates phorbol-ester-, adhesion-dependent and Fc{gamma}-receptor-stimulated ROS production in neutrophils
Laura J Norton, Qifeng Zhang, Khalid M Saqib, et al.
Page
of 57
Search research articles
Search
Showing results (281-290 of 570) with videos related to
Sort By:
Page
of 57
Cell Reports
|
November 3, 2021
mGlu<sub>1</sub> potentiation enhances prelimbic somatostatin interneuron activity to rescue schizophrenia-like physiological and cognitive deficits
James Maksymetz, Nellie E Byun, Deborah J Luessen, et al.
Frontiers in Pharmacology
|
January 26, 2012
Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1
Rene Raphemot, Daniel F Lonergan, Thuy T Nguyen, et al.
The Journal of Biological Chemistry
|
July 29, 2014
Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition
Thomas H Oguin, Shalini Sharma, Amanda D Stuart, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 30, 2020
Lead optimization of the VU0486321 series of mGlu<sub>1</sub> PAMs. Part 4: SAR reveals positive cooperativity across multiple mGlu receptor subtypes leading to subtype unselective PAMs
Dexter C Davis, Joseph D Bungard, Sichen Chang, et al.
Prostaglandins & Other Lipid Mediators
|
July 6, 2019
The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity
Ryan P Ceddia, Jason D Downey, Ryan D Morrison, et al.
Journal of Medicinal Chemistry
|
June 13, 2018
Sterol 14α-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis
Laura Friggeri, Tatiana Y Hargrove, Zdzislaw Wawrzak, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 11, 2019
Towards a TREK-1/2 (TWIK-Related K+ Channel 1 and 2) dual activator tool compound: Multi-dimensional optimization of BL-1249
Yuzo Iwaki, Kentaro Yashiro, Masaya Kokubo, et al.
ACS Chemical Neuroscience
|
April 24, 2010
Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening
Ralf Mueller, Alice L Rodriguez, Eric S Dawson, et al.
Journal of Medicinal Chemistry
|
August 3, 2016
Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1H-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with in Vivo Utility and Activity Against γ-Thrombin
Kayla J Temple, Matthew T Duvernay, Summer E Young, et al.
Journal of Cell Science
|
May 26, 2011
PLD1 rather than PLD2 regulates phorbol-ester-, adhesion-dependent and Fc{gamma}-receptor-stimulated ROS production in neutrophils
Laura J Norton, Qifeng Zhang, Khalid M Saqib, et al.
Page
of 57