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W Lindsley

Showing results (321-330 of 570) with videos related to

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ACS Chemical Neuroscience|September 14, 2010
Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulationAlbert A Davis, Craig J Heilman, Ashley E Brady, et al.
Nature Chemical Biology|January 13, 2009
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasivenessSarah A Scott, Paige E Selvy, Jason R Buck, et al.
Bioorganic & Medicinal Chemistry Letters|April 30, 2018
Discovery of 6-(pyrimidin-5-ylmethyl)quinoline-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
ACS Chemical Neuroscience|January 7, 2015
Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporterElizabeth A Ennis, Jane Wright, Cassandra L Retzlaff, et al.
Bioorganic & Medicinal Chemistry Letters|December 28, 2014
Further optimization of the M5 NAM MLPCN probe ML375: tactics and challengesHaruto Kurata, Patrick R Gentry, Masaya Kokubo, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|January 8, 2016
An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in SchizophreniaDarrick T Balu, Yan Li, Shunsuke Takagi, et al.
ACS Chemical Neuroscience|December 22, 2012
Chemical modification of the M(1) agonist VU0364572 reveals molecular switches in pharmacology and a bitopic binding modeGregory J Digby, Thomas J Utley, Atin Lamsal, et al.
Bioorganic & Medicinal Chemistry Letters|September 22, 2006
Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamidesZhijian Zhao, Julie A O'Brien, Wei Lemaire, et al.
Molecular Pharmacology|March 17, 2018
Differential Pharmacology and Binding of mGlu<sub>2</sub> Receptor Allosteric ModulatorsDaniel E O'Brien, Douglas M Shaw, Hyekyung P Cho, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2005
Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitorsCraig W Lindsley, Zhijian Zhao, William H Leister, et al.
Pageof 57

Showing results (321-330 of 570) with videos related to

Sort By:
Pageof 57
ACS Chemical Neuroscience|September 14, 2010
Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulationAlbert A Davis, Craig J Heilman, Ashley E Brady, et al.
Nature Chemical Biology|January 13, 2009
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasivenessSarah A Scott, Paige E Selvy, Jason R Buck, et al.
Bioorganic & Medicinal Chemistry Letters|April 30, 2018
Discovery of 6-(pyrimidin-5-ylmethyl)quinoline-8-carboxamide negative allosteric modulators of metabotropic glutamate receptor subtype 5Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
ACS Chemical Neuroscience|January 7, 2015
Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporterElizabeth A Ennis, Jane Wright, Cassandra L Retzlaff, et al.
Bioorganic & Medicinal Chemistry Letters|December 28, 2014
Further optimization of the M5 NAM MLPCN probe ML375: tactics and challengesHaruto Kurata, Patrick R Gentry, Masaya Kokubo, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|January 8, 2016
An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in SchizophreniaDarrick T Balu, Yan Li, Shunsuke Takagi, et al.
ACS Chemical Neuroscience|December 22, 2012
Chemical modification of the M(1) agonist VU0364572 reveals molecular switches in pharmacology and a bitopic binding modeGregory J Digby, Thomas J Utley, Atin Lamsal, et al.
Bioorganic & Medicinal Chemistry Letters|September 22, 2006
Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamidesZhijian Zhao, Julie A O'Brien, Wei Lemaire, et al.
Molecular Pharmacology|March 17, 2018
Differential Pharmacology and Binding of mGlu<sub>2</sub> Receptor Allosteric ModulatorsDaniel E O'Brien, Douglas M Shaw, Hyekyung P Cho, et al.
Bioorganic & Medicinal Chemistry Letters|January 25, 2005
Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitorsCraig W Lindsley, Zhijian Zhao, William H Leister, et al.
Pageof 57