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Showing results (371-380 of 570) with videos related to

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Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|March 20, 2009
mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learningJennifer E Ayala, Yelin Chen, Jessica L Banko, et al.
Bioorganic & Medicinal Chemistry Letters|September 23, 2008
Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moietiesThomas M Bridges, Ashley E Brady, J Phillip Kennedy, et al.
Cellular Signalling|September 18, 2013
Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assayAndrew J Storaska, Jian P Mei, Meng Wu, et al.
Bioorganic & Medicinal Chemistry Letters|November 18, 2018
Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5Andrew S Felts, Katrina A Bollinger, Christopher J Brassard, et al.
Bioorganic & Medicinal Chemistry Letters|June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in ratsKimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Neurochemistry International|October 5, 2013
Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor functionChristine Saunders, Michael Siuta, Sabrina D Robertson, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2022
Discovery of a potent M<sub>5</sub> antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonistsRory A Capstick, David Whomble, Douglas L Orsi, et al.
Bioorganic & Medicinal Chemistry Letters|May 14, 2016
Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetrationJoseph D Panarese, Hykeyung P Cho, Jeffrey J Adams, et al.
Bioorganic & Medicinal Chemistry Letters|May 29, 2016
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Rocco D Gogliotti, Anna L Blobaum, Ryan M Morrison, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonistsAaron M Bender, Rebecca L Weiner, Vincent B Luscombe, et al.
Pageof 57

Showing results (371-380 of 570) with videos related to

Sort By:
Pageof 57
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|March 20, 2009
mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learningJennifer E Ayala, Yelin Chen, Jessica L Banko, et al.
Bioorganic & Medicinal Chemistry Letters|September 23, 2008
Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moietiesThomas M Bridges, Ashley E Brady, J Phillip Kennedy, et al.
Cellular Signalling|September 18, 2013
Reversible inhibitors of regulators of G-protein signaling identified in a high-throughput cell-based calcium signaling assayAndrew J Storaska, Jian P Mei, Meng Wu, et al.
Bioorganic & Medicinal Chemistry Letters|November 18, 2018
Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5Andrew S Felts, Katrina A Bollinger, Christopher J Brassard, et al.
Bioorganic & Medicinal Chemistry Letters|June 4, 2013
N-Acyl-N'-arylpiperazines as negative allosteric modulators of mGlu1: identification of VU0469650, a potent and selective tool compound with CNS exposure in ratsKimberly M Lovell, Andrew S Felts, Alice L Rodriguez, et al.
Neurochemistry International|October 5, 2013
Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor functionChristine Saunders, Michael Siuta, Sabrina D Robertson, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2022
Discovery of a potent M<sub>5</sub> antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonistsRory A Capstick, David Whomble, Douglas L Orsi, et al.
Bioorganic & Medicinal Chemistry Letters|May 14, 2016
Further optimization of the M1 PAM VU0453595: Discovery of novel heterobicyclic core motifs with improved CNS penetrationJoseph D Panarese, Hykeyung P Cho, Jeffrey J Adams, et al.
Bioorganic & Medicinal Chemistry Letters|May 29, 2016
Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Rocco D Gogliotti, Anna L Blobaum, Ryan M Morrison, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery and optimization of 3-(4-aryl/heteroarylsulfonyl)piperazin-1-yl)-6-(piperidin-1-yl)pyridazines as novel, CNS penetrant pan-muscarinic antagonistsAaron M Bender, Rebecca L Weiner, Vincent B Luscombe, et al.
Pageof 57