Search research articles
Contact Us
Filters
Showing results (381-390 of 570) with videos related to
Page
of 57
Sort By:
Bioorganic & Medicinal Chemistry Letters
|
December 25, 2018
Novel M<sub>4</sub> positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands
Michael S Poslusney, James M Salovich, Michael R Wood, et al.
Molecular Cancer Therapeutics
|
February 17, 2005
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members
Deborah DeFeo-Jones, Stanley F Barnett, Sheng Fu, et al.
ACS Chemical Neuroscience
|
May 21, 2013
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction
Russell J Amato, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 19, 2016
N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
June 16, 2019
Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063
Sujay V Kharade, Juan Vicente Sanchez-Andres, Mark G Fulton, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2013
Discovery of ML326: The first sub-micromolar, selective M5 PAM
Patrick R Gentry, Thomas M Bridges, Atin Lamsal, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 26, 2023
Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTS
Cayden J Dodd, Keagan S Chronister, Upendra Rathnayake, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 8, 2008
Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists
L Michelle Lewis, Douglas Sheffler, Richard Williams, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
September 23, 2014
Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profiles
Jerri M Rook, Mohammed N Tantawy, Mohammad S Ansari, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2017
Discovery of a novel, CNS penetrant M<sub>4</sub> PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core
Blake R Bewley, Paul K Spearing, Rebecca L Weiner, et al.
Page
of 57
Search research articles
Search
Showing results (381-390 of 570) with videos related to
Sort By:
Page
of 57
Bioorganic & Medicinal Chemistry Letters
|
December 25, 2018
Novel M<sub>4</sub> positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands
Michael S Poslusney, James M Salovich, Michael R Wood, et al.
Molecular Cancer Therapeutics
|
February 17, 2005
Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members
Deborah DeFeo-Jones, Stanley F Barnett, Sheng Fu, et al.
ACS Chemical Neuroscience
|
May 21, 2013
Substituted 1-Phenyl-3-(pyridin-2-yl)urea negative allosteric modulators of mGlu5: discovery of a new tool compound VU0463841 with activity in rat models of cocaine addiction
Russell J Amato, Andrew S Felts, Alice L Rodriguez, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 19, 2016
N-Alkylpyrido[1',2':1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu1/5 with CNS exposure in rodents
Andrew S Felts, Alice L Rodriguez, Ryan D Morrison, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
June 16, 2019
Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063
Sujay V Kharade, Juan Vicente Sanchez-Andres, Mark G Fulton, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2013
Discovery of ML326: The first sub-micromolar, selective M5 PAM
Patrick R Gentry, Thomas M Bridges, Atin Lamsal, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 26, 2023
Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTS
Cayden J Dodd, Keagan S Chronister, Upendra Rathnayake, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 8, 2008
Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists
L Michelle Lewis, Douglas Sheffler, Richard Williams, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
September 23, 2014
Relationship between in vivo receptor occupancy and efficacy of metabotropic glutamate receptor subtype 5 allosteric modulators with different in vitro binding profiles
Jerri M Rook, Mohammed N Tantawy, Mohammad S Ansari, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2017
Discovery of a novel, CNS penetrant M<sub>4</sub> PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core
Blake R Bewley, Paul K Spearing, Rebecca L Weiner, et al.
Page
of 57