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Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
October 9, 2020
A novel allosteric modulator of the cannabinoid CB<sub>1</sub> receptor ameliorates hyperdopaminergia endophenotypes in rodent models
Catharine A Mielnik, Kim S Sugamori, David B Finlay, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 20, 2010
Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis
Alaric J Dyckman, Charles M Langevine, Claude Quesnelle, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 2, 2014
Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases
Qing Shi, Andrew Tebben, Alaric J Dyckman, et al.
Journal of Medicinal Chemistry
|
April 24, 2015
Improving the pharmacokinetic and CYP inhibition profiles of azaxanthene-based glucocorticoid receptor modulators-identification of (S)-5-(2-(9-fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanamido)-N-(tetrahydro-2H-pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341)
Michael G Yang, T G Murali Dhar, Zili Xiao, et al.
Journal of Medicinal Chemistry
|
December 13, 2006
2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor
Jagabandhu Das, Ping Chen, Derek Norris, et al.
Canadian Journal of Kidney Health and Disease
|
September 2, 2021
MyTEMP: Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial
Stephanie N Dixon, Jessica M Sontrop, Ahmed Al-Jaishi, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2011
Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors
Alaric J Dyckman, Tianle Li, Sidney Pitt, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 10, 2006
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
Jagabandhu Das, Joseph A Furch, Chunjian Liu, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 28, 2008
Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38 alpha MAP kinase inhibitors
Stephen T Wrobleski, Shuqun Lin, John Hynes, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
August 5, 2009
Periodic, partial inhibition of IkappaB Kinase beta-mediated signaling yields therapeutic benefit in preclinical models of rheumatoid arthritis
Kathleen M Gillooly, Mark A Pattoli, Tracy L Taylor, et al.
Page
of 51
Search research articles
Search
Showing results (451-460 of 505) with videos related to
Sort By:
Page
of 51
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
October 9, 2020
A novel allosteric modulator of the cannabinoid CB<sub>1</sub> receptor ameliorates hyperdopaminergia endophenotypes in rodent models
Catharine A Mielnik, Kim S Sugamori, David B Finlay, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 20, 2010
Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis
Alaric J Dyckman, Charles M Langevine, Claude Quesnelle, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 2, 2014
Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases
Qing Shi, Andrew Tebben, Alaric J Dyckman, et al.
Journal of Medicinal Chemistry
|
April 24, 2015
Improving the pharmacokinetic and CYP inhibition profiles of azaxanthene-based glucocorticoid receptor modulators-identification of (S)-5-(2-(9-fluoro-2-(4-(2-hydroxypropan-2-yl)phenyl)-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanamido)-N-(tetrahydro-2H-pyran-4-yl)-1,3,4-thiadiazole-2-carboxamide (BMS-341)
Michael G Yang, T G Murali Dhar, Zili Xiao, et al.
Journal of Medicinal Chemistry
|
December 13, 2006
2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor
Jagabandhu Das, Ping Chen, Derek Norris, et al.
Canadian Journal of Kidney Health and Disease
|
September 2, 2021
MyTEMP: Statistical Analysis Plan of a Registry-Based, Cluster-Randomized Clinical Trial
Stephanie N Dixon, Jessica M Sontrop, Ahmed Al-Jaishi, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 28, 2011
Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors
Alaric J Dyckman, Tianle Li, Sidney Pitt, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 10, 2006
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
Jagabandhu Das, Joseph A Furch, Chunjian Liu, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 28, 2008
Synthesis and SAR of new pyrrolo[2,1-f][1,2,4]triazines as potent p38 alpha MAP kinase inhibitors
Stephen T Wrobleski, Shuqun Lin, John Hynes, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
August 5, 2009
Periodic, partial inhibition of IkappaB Kinase beta-mediated signaling yields therapeutic benefit in preclinical models of rheumatoid arthritis
Kathleen M Gillooly, Mark A Pattoli, Tracy L Taylor, et al.
Page
of 51