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ACS Medicinal Chemistry Letters
|
September 18, 2020
Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P<sub>1</sub>) Modulators: Optimization of the PK, PD, and Safety Profiles
Zili Xiao, Michael G Yang, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
June 26, 2007
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)
Scott H Watterson, Ping Chen, Yufen Zhao, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 4, 2008
The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)-A potent and efficacious p38alpha MAP kinase inhibitor
John Hynes, Hong Wu, Sidney Pitt, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 28, 2015
Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity
Paul R Mangan, Linhui Julie Su, Victoria Jenny, et al.
Journal of Immunology (Baltimore, Md. : 1950)
|
December 23, 2016
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
Shailesh Dudhgaonkar, Sourabh Ranade, Jignesh Nagar, et al.
Journal of Medicinal Chemistry
|
January 25, 2021
Bicyclic Ligand-Biased Agonists of S1P<sub>1</sub>: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles
John L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
December 28, 2020
Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2
Chunjian Liu, James Lin, Charles Langevine, et al.
Acta Neuropathologica Communications
|
March 12, 2025
Granular cytoplasmic inclusions in astrocytes and microglial activation in the fetal brain of pigtail macaques in response to maternal viral infection
Raj P Kapur, Andrew E Vo, Amanda Li, et al.
Journal of Medicinal Chemistry
|
August 20, 2004
Imidazoquinoxaline Src-family kinase p56Lck inhibitors: SAR, QSAR, and the discovery of (S)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a potent and orally active inhibitor with excellent in vivo antiinflammatory activity
Ping Chen, Arthur M Doweyko, Derek Norris, et al.
ACS Medicinal Chemistry Letters
|
March 21, 2019
Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis
Steven H Spergel, Michael E Mertzman, James Kempson, et al.
Page
of 51
Search research articles
Search
Showing results (461-470 of 505) with videos related to
Sort By:
Page
of 51
ACS Medicinal Chemistry Letters
|
September 18, 2020
Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P<sub>1</sub>) Modulators: Optimization of the PK, PD, and Safety Profiles
Zili Xiao, Michael G Yang, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
June 26, 2007
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)
Scott H Watterson, Ping Chen, Yufen Zhao, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 4, 2008
The discovery of (R)-2-(sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl) thiazole-5-carboxamide (BMS-640994)-A potent and efficacious p38alpha MAP kinase inhibitor
John Hynes, Hong Wu, Sidney Pitt, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
May 28, 2015
Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity
Paul R Mangan, Linhui Julie Su, Victoria Jenny, et al.
Journal of Immunology (Baltimore, Md. : 1950)
|
December 23, 2016
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
Shailesh Dudhgaonkar, Sourabh Ranade, Jignesh Nagar, et al.
Journal of Medicinal Chemistry
|
January 25, 2021
Bicyclic Ligand-Biased Agonists of S1P<sub>1</sub>: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles
John L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
December 28, 2020
Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2
Chunjian Liu, James Lin, Charles Langevine, et al.
Acta Neuropathologica Communications
|
March 12, 2025
Granular cytoplasmic inclusions in astrocytes and microglial activation in the fetal brain of pigtail macaques in response to maternal viral infection
Raj P Kapur, Andrew E Vo, Amanda Li, et al.
Journal of Medicinal Chemistry
|
August 20, 2004
Imidazoquinoxaline Src-family kinase p56Lck inhibitors: SAR, QSAR, and the discovery of (S)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a potent and orally active inhibitor with excellent in vivo antiinflammatory activity
Ping Chen, Arthur M Doweyko, Derek Norris, et al.
ACS Medicinal Chemistry Letters
|
March 21, 2019
Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis
Steven H Spergel, Michael E Mertzman, James Kempson, et al.
Page
of 51