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W T Ashton

Showing results (1-10 of 38) with videos related to

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Journal of Medicinal Chemistry|November 1, 1970
Irreversible enzyme inhibitors. CLXXVI. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine by ether bridging to a terminal sulfonyl fluorideB R Baker, W T Ashton
Journal of Medicinal Chemistry|March 1, 1973
Irreversible enzyme inhibitors. 197. Water-soluble reversible inhibitors of dihydrofolate reductase with potent antitumor activity derived from 4, 6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazineB R Baker, W T Ashton
Journal of Medicinal Chemistry|September 1, 1974
Quinazolines as inhibitors of dihydrofolate reductase. 2J B Hynes, W T Ashton
Journal of Medicinal Chemistry|March 1, 1975
Synthesis and evaluation of 6-arylactamido-2,4-diaminoquinazolines and related compounds as folic acid antagonistsJ B Hynes, W T Ashton
Journal of Medicinal Chemistry|November 1, 1970
Irreversible enzyme inhibitors. 178. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with a terminal sulfonyl fluorideB R Baker, W T Ashton
Journal of Medicinal Chemistry|November 1, 1973
Synthesis of 5-substituted quinazolines as potential antimalarial agentsW T Ashton, J B Hynes
Journal of Medicinal Chemistry|September 1, 1972
Irreversible enzyme inhibitors. 196. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine and bearing a terminal phenyl sulfonate groupB R Baker, W T Ashton
Journal of Medicinal Chemistry|November 1, 1970
Irreversible enzyme inhibitors. CLXXIX. Active-site-directed irreversible enzyme inhibitors of dihydrofolate reductase from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with oxyamide bridges to a terminal sulfonyl fluorideB R Baker, W T Ashton
Journal of Medicinal Chemistry|December 1, 1972
Synthesis of some bis(2,4-diaminopyrimidines) and bis(2,4-diaminoquinazolines) as potential antimalarial agentsJ B Hynes, R F Gratz, W T Ashton
Journal of Medicinal Chemistry|June 1, 1973
Quinazolines as inhibitors of dihydrofolate reductase. 1W T Ashton, F C Walker, J B Hynes
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Showing results (1-10 of 38) with videos related to

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Journal of Medicinal Chemistry|November 1, 1970
Irreversible enzyme inhibitors. CLXXVI. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine by ether bridging to a terminal sulfonyl fluorideB R Baker, W T Ashton
Journal of Medicinal Chemistry|March 1, 1973
Irreversible enzyme inhibitors. 197. Water-soluble reversible inhibitors of dihydrofolate reductase with potent antitumor activity derived from 4, 6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazineB R Baker, W T Ashton
Journal of Medicinal Chemistry|September 1, 1974
Quinazolines as inhibitors of dihydrofolate reductase. 2J B Hynes, W T Ashton
Journal of Medicinal Chemistry|March 1, 1975
Synthesis and evaluation of 6-arylactamido-2,4-diaminoquinazolines and related compounds as folic acid antagonistsJ B Hynes, W T Ashton
Journal of Medicinal Chemistry|November 1, 1970
Irreversible enzyme inhibitors. 178. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with a terminal sulfonyl fluorideB R Baker, W T Ashton
Journal of Medicinal Chemistry|November 1, 1973
Synthesis of 5-substituted quinazolines as potential antimalarial agentsW T Ashton, J B Hynes
Journal of Medicinal Chemistry|September 1, 1972
Irreversible enzyme inhibitors. 196. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 1-(4-benzyloxy-3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine and bearing a terminal phenyl sulfonate groupB R Baker, W T Ashton
Journal of Medicinal Chemistry|November 1, 1970
Irreversible enzyme inhibitors. CLXXIX. Active-site-directed irreversible enzyme inhibitors of dihydrofolate reductase from 1-(3-chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazine with oxyamide bridges to a terminal sulfonyl fluorideB R Baker, W T Ashton
Journal of Medicinal Chemistry|December 1, 1972
Synthesis of some bis(2,4-diaminopyrimidines) and bis(2,4-diaminoquinazolines) as potential antimalarial agentsJ B Hynes, R F Gratz, W T Ashton
Journal of Medicinal Chemistry|June 1, 1973
Quinazolines as inhibitors of dihydrofolate reductase. 1W T Ashton, F C Walker, J B Hynes
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