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The Journal of Experimental Medicine|March 21, 2019
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AMLFaisal Basheer, George Giotopoulos, Eshwar Meduri, et al.Cancer Cell|February 14, 2018
Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic ProgenitorsChristopher A G Booth, Nikolaos Barkas, Wen Hao Neo, et al.Plos One|March 20, 2014
Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring geneSimon Maguire, Jeanne Estabel, Neil Ingham, et al.Nature Genetics|September 24, 2021
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expressionHaiyang Yun, Nisha Narayan, Shabana Vohra, et al.NEJM Evidence|February 6, 2024
Regulatory T-Cell Response to Low-Dose Interleukin-2 in Ischemic Heart DiseaseTian X Zhao, Rouchelle S Sriranjan, Zewen Kelvin Tuong, et al.Nature Communications|May 20, 2025
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibitionAlicia Garcia-Gimenez, Jonathan E Ditcham, Dhoyazan M A Azazi, et al.Nature Communications|April 14, 2023
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell deathKeith Woodley, Laura S Dillingh, George Giotopoulos, et al.Blood|August 6, 2005
The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemiaRoss L Levine, Marc Loriaux, Brian J P Huntly, et al.Nature Communications|October 6, 2019
Genetic modification of primary human B cells to model high-grade lymphomaRebecca Caeser, Miriam Di Re, Joanna A Krupka, et al.Nature Genetics|August 14, 2023
In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesisDavid Lara-Astiaso, Ainhoa Goñi-Salaverri, Julen Mendieta-Esteban, et al.Pageof 10