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Microbiome|April 21, 2021
The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in miceSharon Ann Barretto, Frederic Lasserre, Marine Huillet, et al.Scientific Reports|April 18, 2020
Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesityMarion Régnier, Arnaud Polizzi, Sarra Smati, et al.Cell Reports|October 12, 2017
A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 ResponseAlison Iroz, Alexandra Montagner, Fadila Benhamed, et al.Cell Discovery|April 6, 2018
Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expressionMing Keat Sng, Jeremy Soon Kiat Chan, Ziqiang Teo, et al.Cell Reports|April 13, 2022
The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expressionTiffany Fougeray, Arnaud Polizzi, Marion Régnier, et al.Journal of Hepatology|January 25, 2019
Hepatic PPARα is critical in the metabolic adaptation to sepsisRéjane Paumelle, Joel T Haas, Nathalie Hennuyer, et al.Nature Communications|May 22, 2026
Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASHDamien Chua, Zun Siong Low, Joseph Han Sol Kim, et al.EMBO Reports|April 27, 2026
Hepatic FGF21 is not required for fasting metabolism but guides protein appetite post energy depletionJustine Bruse, Clothilde Marbach, Arnaud Polizzi, et al.Science Advances|March 25, 2022
Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptorJean Personnaz, Enzo Piccolo, Alizée Dortignac, et al.Cell Reports|June 8, 2022
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activityAnne Fougerat, Gabriele Schoiswohl, Arnaud Polizzi, et al.Pageof 21