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Warren W Ku

Showing results (1-10 of 11) with videos related to

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Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 20, 2020
Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced SteatosisParimal Pande, Xiao-Bo Zhong, Warren W Ku
Current Opinion in Drug Discovery & Development|February 1, 2006
Informed toxicity assessment in drug discovery: systems-based toxicologyJames T Mayne, Warren W Ku, Scott P Kennedy
Journal of Pharmacological and Toxicological Methods|November 12, 2009
A simple orchidometric method for the preliminary assessment of maturity status in male cynomolgus monkeys (Macaca fascicularis) used for nonclinical safety studiesWarren W Ku, Frank Pagliusi, George Foley, et al.
Regulatory Toxicology and Pharmacology : RTP|March 24, 2007
An evaluation of the sensitivity of the Ames assay to discern low-level mutagenic impuritiesMichelle O Kenyon, Jennifer R Cheung, Krista L Dobo, et al.
Regulatory Toxicology and Pharmacology : RTP|February 9, 2006
The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug developmentKrista L Dobo, Nigel Greene, Michelle O Cyr, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|June 6, 2007
Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessmentWarren W Ku, Jiri Aubrecht, Robert J Mauthe, et al.
Mutagenesis|July 28, 2007
Bioluminescent Salmonella reverse mutation assay: a screen for detecting mutagenicity with high throughput attributesJiri Aubrecht, Jeffery J Osowski, Prita Persaud, et al.
Journal of Applied Toxicology : JAT|April 8, 2022
Mode of action and human relevance assessment of male CD-1 mouse renal adenocarcinoma associated with lifetime exposure to empagliflozinJonathan A Phillips, Mitchell E Taub, Matthew S Bogdanffy, et al.
Toxicologic Pathology|June 28, 2018
Pathogenesis of Renal Injury and Gene Expression Changes in the Male CD-1 Mouse Associated with Exposure to EmpagliflozinBrian Knight, Jing Yuan, Sally Koegler, et al.
International Journal of Toxicology|November 14, 2017
A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not GenotoxicJames D Smith, Zimei Huang, Patricia A Escobar, et al.
Pageof 2

Showing results (1-10 of 11) with videos related to

Sort By:
Pageof 2
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 20, 2020
Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced SteatosisParimal Pande, Xiao-Bo Zhong, Warren W Ku
Current Opinion in Drug Discovery & Development|February 1, 2006
Informed toxicity assessment in drug discovery: systems-based toxicologyJames T Mayne, Warren W Ku, Scott P Kennedy
Journal of Pharmacological and Toxicological Methods|November 12, 2009
A simple orchidometric method for the preliminary assessment of maturity status in male cynomolgus monkeys (Macaca fascicularis) used for nonclinical safety studiesWarren W Ku, Frank Pagliusi, George Foley, et al.
Regulatory Toxicology and Pharmacology : RTP|March 24, 2007
An evaluation of the sensitivity of the Ames assay to discern low-level mutagenic impuritiesMichelle O Kenyon, Jennifer R Cheung, Krista L Dobo, et al.
Regulatory Toxicology and Pharmacology : RTP|February 9, 2006
The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug developmentKrista L Dobo, Nigel Greene, Michelle O Cyr, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|June 6, 2007
Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessmentWarren W Ku, Jiri Aubrecht, Robert J Mauthe, et al.
Mutagenesis|July 28, 2007
Bioluminescent Salmonella reverse mutation assay: a screen for detecting mutagenicity with high throughput attributesJiri Aubrecht, Jeffery J Osowski, Prita Persaud, et al.
Journal of Applied Toxicology : JAT|April 8, 2022
Mode of action and human relevance assessment of male CD-1 mouse renal adenocarcinoma associated with lifetime exposure to empagliflozinJonathan A Phillips, Mitchell E Taub, Matthew S Bogdanffy, et al.
Toxicologic Pathology|June 28, 2018
Pathogenesis of Renal Injury and Gene Expression Changes in the Male CD-1 Mouse Associated with Exposure to EmpagliflozinBrian Knight, Jing Yuan, Sally Koegler, et al.
International Journal of Toxicology|November 14, 2017
A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not GenotoxicJames D Smith, Zimei Huang, Patricia A Escobar, et al.
Pageof 2