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Methods in Enzymology|August 29, 2019
Measuring TREX1 and TREX2 exonuclease activitiesWayne O Hemphill, Fred W Perrino
DNA Repair|July 3, 2020
TREX1 - Apex predator of cytosolic DNA metabolismSean R Simpson, Wayne O Hemphill, Teesha Hudson, et al.
Frontiers in Immunology|April 19, 2021
TREX1 as a Novel Immunotherapeutic TargetWayne O Hemphill, Sean R Simpson, Mingyong Liu, et al.
Autoimmunity|November 14, 2018
TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesisStephen L Rego, Scott Harvey, Sean R Simpson, et al.
Journal of Immunology (Baltimore, Md. : 1950)|December 13, 2019
T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like AutoimmunitySean R Simpson, Stephen L Rego, Scott E Harvey, et al.
The Biochemical Journal|September 9, 2004
Dysfunctional proofreading in the Escherichia coli DNA polymerase III coreDuane A Lehtinen, Fred W Perrino
Biochemistry|November 1, 2018
Identification of Inhibitors of the dNTP Triphosphohydrolase SAMHD1 Using a Novel and Direct High-Throughput AssayChristopher H Mauney, Fred W Perrino, Thomas Hollis
Nucleic Acids Research|March 27, 2009
DNA binding induces active site conformational change in the human TREX2 3'-exonucleaseUdesh de Silva, Fred W Perrino, Thomas Hollis
The Journal of Biological Chemistry|April 2, 2011
Functional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndromeStephanie R Coffin, Thomas Hollis, Fred W Perrino
The Journal of Biological Chemistry|January 22, 2005
The human TREX2 3' -> 5'-exonuclease structure suggests a mechanism for efficient nonprocessive DNA catalysisFred W Perrino, Scott Harvey, Sara McMillin, et al.
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