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Bioorganic & Medicinal Chemistry Letters|February 7, 2006
Inhibitors of human mitotic kinesin Eg5: characterization of the 4-phenyl-tetrahydroisoquinoline lead seriesChristine M Tarby, Robert F Kaltenbach, Tram Huynh, et al.Journal of Medicinal Chemistry|November 16, 2010
Dimethyl-diphenyl-propanamide derivatives as nonsteroidal dissociated glucocorticoid receptor agonistsBingwei V Yang, David S Weinstein, Lidia M Doweyko, et al.Analytical Biochemistry|June 6, 2009
Assessing compound binding to the Eg5 motor domain using a thermal shift assayPatricia A McDonnell, Joseph Yanchunas, John A Newitt, et al.Bioorganic & Medicinal Chemistry Letters|February 22, 2008
Identification of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of Met kinaseGretchen M Schroeder, Xiao-Tao Chen, David K Williams, et al.Journal of Medicinal Chemistry|April 22, 2010
Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521)Scott H Watterson, Zili Xiao, Dharmpal S Dodd, et al.Journal of Medicinal Chemistry|September 20, 2021
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug DesignAshvinikumar V Gavai, Derek Norris, George Delucca, et al.Nature Communications|January 31, 2026
Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12CMatthew L Condakes, Zhuo Zhang, Derek B Danahy, et al.Pageof 3