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Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|November 26, 2024
Discovery of dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitors using an artificial intelligence model and their effects on tau and tubulin dynamicsJun-Hong Chen, Huang-Ju Tu, Tony Eight Lin, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry|November 10, 2020
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approachMin-Wu Chao, Tony Eight Lin, Wei-Chun HuangFu, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|December 30, 2021
Identification and analysis of a selective DYRK1A inhibitorTony Eight Lin, Min-Wu Chao, Wei-Chun HuangFu, et al.
International Journal of Biological Macromolecules|November 8, 2024
Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinomaWan-Hsi Shih, Han-Li Huang, Wei-Chun HuangFu, et al.
European Journal of Medicinal Chemistry|November 26, 2016
3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activityHsueh-Yun Lee, Jiann-Fong Lee, Sunil Kumar, et al.
International Journal of Biological Macromolecules|October 31, 2024
Identification, biological evaluation, and crystallographic analysis of coumestrol as a novel dual-specificity tyrosine-phosphorylation-regulated kinase 1A inhibitorChao-Hsiang Peng, Tsong-Long Hwang, Shao-Chi Hung, et al.
Bioorganic Chemistry|February 19, 2022
Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approachShih-Chung Yen, Liang-Chieh Chen, Han-Li Huang, et al.
Journal of Natural Products|October 7, 2020
Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid LeukemiaLiang-Chieh Chen, Han-Li Huang, Wei-Chun HuangFu, et al.
Oncotarget|February 11, 2017
An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cellsMin-Wu Chao, Han-Li Huang, Wei-Chun HuangFu, et al.
Phytomedicine : International Journal of Phytotherapy and Phytopharmacology|April 1, 2022
O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemiaShih-Chung Yen, Yi-Wen Wu, Cheng-Chiao Huang, et al.
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