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Cell Reports|April 4, 2025
Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell developmentSeung Kyu Lee, Weiping Shen, William Wen, et al.
Nature Communications|November 25, 2018
Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in DrosophilaSeung Kyu Lee, Yutong Xue, Weiping Shen, et al.
Molecular Cell|June 19, 2012
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair networkZhijiang Yan, Rong Guo, Manikandan Paramasivam, et al.
The Journal of Biological Chemistry|August 2, 2025
Discovery of thiacyanine dyes as a new class of potent coronavirus inhibitors that suppress viral RNA synthesisTianyi Zhang, Valerie Altouma, Joshua A Sommers, et al.
Nucleic Acids Research|June 4, 2016
RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animalsMuzammil Ahmad, Yutong Xue, Seung Kyu Lee, et al.
Nature Neuroscience|August 6, 2013
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formationDongyi Xu, Weiping Shen, Rong Guo, et al.
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