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Science Translational Medicine
|
May 27, 2011
A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo
Jasvinder K Atwal, Yongmei Chen, Cecilia Chiu, et al.
Omics : a Journal of Integrative Biology
|
May 9, 2017
Next-Generation Sequencing Reveals Novel Mutations in X-linked Intellectual Disability
Babylakshmi Muthusamy, Lakshmi Dhevi N Selvan, Thong T Nguyen, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
March 21, 2012
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Till Maurer, Lindsay S Garrenton, Angela Oh, et al.
ACS Medicinal Chemistry Letters
|
May 31, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor
Malcolm P Huestis, Matthew R Durk, Charles Eigenbrot, et al.
Journal of Medicinal Chemistry
|
April 27, 2013
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 2, 2013
Development and preclinical characterization of a humanized antibody targeting CXCL12
Cuiling Zhong, Jianyong Wang, Bing Li, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 13, 2014
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2
James F Blake, John J Gaudino, Jason De Meese, et al.
Journal of Medicinal Chemistry
|
January 18, 2014
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type I 1/2 kinase inhibitors
Steven T Staben, Jianwen A Feng, Karen Lyle, et al.
Journal of Medicinal Chemistry
|
March 29, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3<i>H</i>)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor
Malcolm P Huestis, Darlene Dela Cruz, Antonio G DiPasquale, et al.
Journal of Medicinal Chemistry
|
May 15, 2024
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model
Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, et al.
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Search research articles
Search
Showing results (61-70 of 91) with videos related to
Sort By:
Page
of 10
Science Translational Medicine
|
May 27, 2011
A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo
Jasvinder K Atwal, Yongmei Chen, Cecilia Chiu, et al.
Omics : a Journal of Integrative Biology
|
May 9, 2017
Next-Generation Sequencing Reveals Novel Mutations in X-linked Intellectual Disability
Babylakshmi Muthusamy, Lakshmi Dhevi N Selvan, Thong T Nguyen, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
March 21, 2012
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity
Till Maurer, Lindsay S Garrenton, Angela Oh, et al.
ACS Medicinal Chemistry Letters
|
May 31, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor
Malcolm P Huestis, Matthew R Durk, Charles Eigenbrot, et al.
Journal of Medicinal Chemistry
|
April 27, 2013
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
July 2, 2013
Development and preclinical characterization of a humanized antibody targeting CXCL12
Cuiling Zhong, Jianyong Wang, Bing Li, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 13, 2014
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2
James F Blake, John J Gaudino, Jason De Meese, et al.
Journal of Medicinal Chemistry
|
January 18, 2014
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type I 1/2 kinase inhibitors
Steven T Staben, Jianwen A Feng, Karen Lyle, et al.
Journal of Medicinal Chemistry
|
March 29, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3<i>H</i>)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor
Malcolm P Huestis, Darlene Dela Cruz, Antonio G DiPasquale, et al.
Journal of Medicinal Chemistry
|
May 15, 2024
Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model
Marie-Gabrielle Braun, Avi Ashkenazi, Ramsay E Beveridge, et al.
Page
of 10